Comparison of Anti Thyroid Peroxidase Antibody (TPOAb) levels in people with depression and healthy people: case control-study

نویسندگان

Ramezani, Majid Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

چکیده مقاله:

Background and Aim: Depression is a common psychiatric disorder with a high prevalence in military personnel. Recently, the relationship between depression and some hormones has been reported. In current study, the serum levels of anti-thyroid peroxidase (anti-TPO), triiodothyronine (T3), thyroxin (T4) and thyroid-stimulating hormone (TSH) was assessed in people with depression and compared with healthy control adults. Methods: In this case–control study, 45 people with depression who were diagnosed using the Beck depression test and DSM5, were referred to a military hospital. A total of 45 healthy participants who were matched according gender and age with the depression group, were also enrolled. Levels of anti-TPO, T4, T3 and TSH were measured and compared in the two groups. Results: The mean ±standard deviation age was 36.55±11.42 years in the case group and 35.92±11.58 years in the matched control group. There was no significant difference in the mean serum level of antithyroid peroxidase, T3, T4 and TSH between the groups (P≥0.05). There was no linear correlation between antithyroid peroxidase levels and depression severity. Conclusion: As there was not difference regarding anti-TPO antibody levels between the depressed and healthy groups, it appears that anti-TPO antibody may not have a role in depression.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparison of Coping Strategies in People with Inflammatory Bowel Disease and Healthy People in Terms of Health Locus of Control

Background: Inflammatory bowel disease (IBD) is a group of disorders that cause chronic inflammation (pain and swelling) in the intestines. IBD includes Crohn’s disease and ulcerative colitis. Both types affect the digestive system. The study aims to compare coping strategies in people with inflammatory bowel disease and healthy people, according to internal and external sources of health contr...

متن کامل

Relationship between Anti-Thyroid Peroxidase Antibody and Thyroid Function Test

Background: Anti-thyroid peroxidase antibody (anti-TPO antibody) is a member of thyroid autoantibodies which are important in inducing and also diagnosing autoimmune thyroid diseases. Thyroid autoimmunity can cause several forms of thyroiditis and abnormal thyroid functions, ranging from hypothyroidism to hyperthyroidism. Objective: To evaluate the relationship between serum levels of anti-TPO ...

متن کامل

Comparison of Serum Strontium and Antimony Levels in Patients with Esophageal Cancer and Healthy People

ABSTRACT        Background and Objective: Esophageal cancer is the third most common type of cancer in Iran. Studies on water, soil, grains, waste and sediments in Golestan Province have shown that the environmental concentrations of antimony and strontium are increased in areas with high incidence rate for cancer. The carcinogenic effects of strontium have be...

متن کامل

Comparison of Salivary Peroxidase in HIV Positive Patients and Healthy Controls: A Case-Control Study

Background and Aim: Saliva, as an easy diagnostic tool, has various defense mecha-nisms such as immunological, enzymatic and antioxidant defense systems. Salivary peroxidase is one of the most important salivary antioxidants. Human immunodeficiency virus (HIV) positive and acquired immunodeficiency syndrome (AIDS) patients have decreased antioxidant and increased oxidative stress levels. Theref...

متن کامل