Efficient one-pot synthesis of 6-amino-4-aryl-5-cyano-2-methyl-4H-pyran-3-carboxylates catalyzed by nano MgO in water
نویسندگان
چکیده مقاله:
Water is a versatile solvent in many ways, and in this sense performing organic reactions in this medium is now of great interest. The one-pot reaction of ethyl acetoacetate or benzyl acetoacetate, with benzaldehydes and malononitrile to provide some novel 6-amino-4-aryl-5-cyano-2-methyl-4H-pyran-3-carboxylates has been performed over nano MgO with high performance in water as a green solvent at 80 °C. The nanocrystalline MgO catalyst was characterized via X-ray diffraction (XRD), transmission electron microscopy (TEM) and BET analysis. This method offers considerable improvements for the synthesis of 6-amino-4-aryl-5-cyano-2-methyl-4H-pyran-3-carboxylates with concern to the yield of products, facility in operation, and green aspects without using of toxic catalysts and solvents.
منابع مشابه
Triphenylphosphine Catalysed Facile Multicomponent Synthesis of 2-Amino-3-Cyano-6-Methyl-4-Aryl-4H-Pyrans
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عنوان ژورنال
دوره 6 شماره Issue 2, pp. 109-217
صفحات 125- 133
تاریخ انتشار 2018-04-01
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