Evaluation of the anti–depressant activity of Myristica fragrans (Nutmeg) in male rats
نویسندگان
چکیده مقاله:
Objective: The present study was undertaken to evaluate anti-depressant activity of Myristica fragrans(MS). Materials and Methods: Male Wistar rats were subjected to imipramine and herbal extract ofMS for their antidepressant activity using Forced Swimming Test (FST), Reserpine Reversal Test (RRT), Haloperidol-Induced Catalepsy (HIC), and Pentobarbitone Sleeping Time (PST). Results: Administration of MS and imipramine revealed a statistically significant reduction in immobility time in FST, RRT, and protection against HIC, compared to the control group. However, there was no significant potentiation of PST. Conclusion: Our study demonstrated the potential antidepressant activity of MS.
منابع مشابه
evaluation of the anti–depressant activity of myristica fragrans (nutmeg) in male rats
objective: the present study was undertaken to evaluate anti-depressant activity of myristica fragrans(ms). materials and methods: male wistar rats were subjected to imipramine and herbal extract ofms for their antidepressant activity using forced swimming test (fst), reserpine reversal test (rrt), haloperidol-induced catalepsy (hic), and pentobarbitone sleeping time (pst). results: administrat...
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عنوان ژورنال
دوره 2 شماره 2
صفحات 72- 78
تاریخ انتشار 2012-03-01
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