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Molecular biomarkers in thyroid FNA samples.
In this issue of the JCEM, Walsh et al. (1) report the analytical validation of a molecular diagnostic method for indeterminate fine-needle aspiration (FNA) thyroid samples. Together with previous reports describing clinical performance and cost effectiveness of this method, this study highlights the capability of such a molecular test to reduce unnecessary surgery for benign thyroid diseases (...
متن کاملFine-needle aspiration (FNA) biopsy: historical aspects.
This study aims to present the origins and the historical evolution of fine-needle aspiration biopsy and to also underline its importance in the history of modern cytology. The article focuses on the advances made in the 20th century that have led to the modern techniques associated with the procedure. The authors conducted a thorough review of early reports on needle biopsy, particularly those...
متن کاملPancreas cystic lymphangioma diagnosed with EUS-FNA.
CONTEXT Endoscopic ultrasound has proved to be an invaluable tool when obtaining high quality images of the pancreas. Furthermore, fine-needle aspiration of suspected lesions can be carried out simultaneously thus providing tissue samples for cytologic diagnosis. We present two cases of a rare pancreatic lesion that were diagnosed by endoscopic ultrasound with fine-needle aspiration. CASE #1: A...
متن کاملSalivary Gland FNA: Anatomic, Clinical, and Technical Considerations
The major salivary glands consist of the parotid, the submandibular, and the sublingual glands. Under the control of the parasympathetic nervous system, the major salivary glands are responsible for the principal portion of saliva produced, which can be as much as 1.5 liters per day. The minor salivary glands of the oral cavity, pharynx, and upper airways contribute only a small percentage of t...
متن کاملEUS-FNA for the Diagnosis of Retroperitoneal Primitive Neuroectodermal Tumor
Primitive neuroectodermal tumor (PNET) is a rare "small round blue cell tumor" that is diagnosed by open biopsy or percutaneous biopsy of the lesion under radiologic guidance. In this case report, we present a novel approach to the diagnosis of a retroperitoneal PNET by endoscopic ultrasound- (EUS-) guided fine needle aspiration (FNA). A 35-year-old man presented with the history of left-sided ...
متن کاملFalse-positive FNA due to highly sensitive BRAF assay.
OBJECTIVE False-positive BRAF analysis on fine-needle aspiration (FNA) has rarely been reported in the literature but may become more common with the advent of assays that can detect the BRAF V600E mutation in only 2% of otherwise wild-type thyroid cells. We present the case of an indeterminate BRAF-positive FNA that showed no evidence of cancer on final surgical pathology. METHODS Case repor...
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عنوان ژورنال
دوره 5 شماره None
صفحات 9- 15
تاریخ انتشار 2000-06
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