Human T Lymphotropic Virus Type I (HTLV-I) is a Risk Factor for Coronary Artery Disease


  • Farahzad Jabbari Allergy Research Centre
  • Farnaz Mozayani Immunology Research Centre
  • Mahmoud Shabestari Preventive Cardiovascular Care Research Centre
  • Mansoreh Sobhani Allergy Research Centre
  • Narges Valizadeh Inflammation and Inflammation diseases Research Centre
  • Reza Farid Hosseni Immunology Research Centre
  • S. A. Rahim Rezaee Inflammation and Inflammation diseases Research Centre
  • Yousef Gharivani Preventive Cardiovascular Care Research Centre
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Human T Lymphotropic Virus Type I (HTLV-I) is a Risk Factor for Coronary Artery Disease

OBJECTIVE(S) Few studies have shown the association between HTLV-I infection and coronary artery disease (CAD). HTLV-I has been detected in heart autopsies, particularly in lymphoma\leukemia cases. Mashhad and Neyshabour (Razavi Khorasan Province, Iran) are endemic regions for HTLV-I. Therefore, the present study was carried out to evaluate the impact of HTLV-I on CAD in Neyshabourian patients....

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Human T Lymphotropic Virus Type I (HTLV-I) Oncogenesis: Molecular Aspects of Virus and Host Interactions in Pathogenesis of Adult T cell Leukemia/Lymphoma (ATL)

    The study of tumor viruses paves the way for understanding the mechanisms of virus pathogenesis, including those involved in establishing infection and dissemination in the host tumor affecting immune-compromised patients. The processes ranging from viral infection to progressing malignancy are slow and usually insufficient for establishment of transformed cells that develop cancer in only ...

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Polymorphism in the interleukin-10 promoter affects both provirus load and the risk of human t lymphotropic virus type I (HTLV-I) associated myelopathy/tropical spastic paraparesis

To investigate candidate genes that influence the risk of HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP), we analyzed 6 single nucleotide polymorphisms (SNP) in the interleukin-10 (IL-10) promoter region. METHODS: 280 cases of HAM/TSP patients and 255 HTLV-I seropositive asymptomatic carriers (HCs) from Kagoshima, Japan were studied. All subjects gave written informed conse...

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عنوان ژورنال

دوره 16  شماره 3

صفحات  224- 227

تاریخ انتشار 2013-03-01

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