Hypotensive effect of Achillea wilhelmsii aqueous-ethanolic extract in rabbit

نویسندگان

  • F. Harandizadeh Department of Biology, School of Sciences, Ferdowsi University. Mashhad, I. R. Iran
  • M. Esparham Department of Biology, School of Sciences, Islamic Azad University, Mashhad Branch, I. R. Iran
  • S. A. Rezaee Department of Immunology, School of Medicine, Mashhad University of Medical Sciences Mashhad, I. R. Iran
  • Saeed Niazmand Department of Physiology and Cardiovascular Research Center, School of Medicine Mashhad University of Medical Sciences Mashhad, I. R. Iran
چکیده مقاله:

Objective: For many years in herbal medicine the antihypertensive and lowering blood lipid properties of Achillea wilhelmsii (A. wilhelmsii) have been suggested. In the present study the impacts of the plant extract on rabbit’s blood pressure and heart rate have been investigated. Materials and Methods: Twelve NWZ rabbits weighed 2-3 kg were randomly divided into two groups of 6 rabbits. The test group received A. wilhelmsii extract (20, 40 and 80 mg/kg) and the control group received normal saline by jugular vein cannula. Blood pressure and heart rate were measured via carotid cannula using pressure transducer connected to a power lab system. Results: The blood pressure was significantly decreased (16.7± 1.4 mmHg) in 80 mg/kg dose of the extract (p

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hypotensive effect of achillea wilhelmsii aqueous-ethanolic extract in rabbit

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عنوان ژورنال

دوره 1  شماره 1

صفحات  51- 56

تاریخ انتشار 2011-06-01

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