P-159: Women's Infertility and Polycystic Ovarian Syndrome, Concepts and Treatment
نویسندگان
چکیده مقاله:
Background: Polycystic ovarian syndrome (PCOS) is a medical condition that affects women's menstrual cycles, fertility, hormone levels, and physical appearance. PCOS is thought to be one of the leading causes of female infertility, and is the reason of more than 75% of cases of anovulatory infertility. Materials and Methods: In this article, we review the different aspects of PCOS including genetic biasis and treatment. Results: The mechanism of anovulation is uncertain, but there is evidence that arrested antral follicle development is associated with the abnormal endocrine profile, in particular the interaction of insulin and LH on granulosa cell differentiation. Clinical evidence indicates that polycystic ovary syndrome has a heritable basis, at least in part, which could result from a genetic etiology, epigenetic changes, or an admixture of the two causes. Conclusion: Although, there is no cure for PCOS, but controlling it lowers the PCOS risks of infertility, miscarriages, diabetes, heart disease, and uterine cancer. Management of infertility in polycystic ovary syndrome includes lifestyle modification as well as assisted reproductive technology such as ovulation induction, oocyte release triggering and surgery.
منابع مشابه
Polycystic ovarian syndrome in infertility
Polycystic ovarian syndrome (PCOS) is a condition of unexplained hyperandrogenic chronic anovulation that most likely represents a heterogenous disorder. About 10% of women in the reproductive age group suffer from this disorder. Many adolescent girls and young adults seek consultation because of this disorder. It’s etiology is as yet undefined, and therapy remains largely symptomatic and empir...
متن کاملGestational diabetes after infertility treatment for polycystic ovarian syndrome.
P ovarian syndrome (PCOS) and gestational diabetes (GDM) are both insulin resistant conditions. Women with PCOS are at least twice as likely to develop GDM; they may be infertile and need to seek medical assistance to conceive. Fetal and maternal outcomes of assisted pregnancies in the setting of PCOS are unknown. We propose to document in a retrospective study, pregnancy outcomes in women with...
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Polycystic ovarian syndrome is a hormonal disturbance that results in a collection of symptoms and has wide-ranging health implications. There is evidence that it may run in families, and it is associated with the development of type 2 diabetes and recurrent miscarriage. Diagnosis involves eliminating other potential conditions, while treatment aims to manage individual symptoms rather than pro...
متن کاملMetformin and troglitazone in the treatment of female infertility associated with polycystic ovarian syndrome.
Polycystic ovarian syndrome is the most common cause of anovulatory infertility and causes menstrual disruption in 5-10% females, and is characterized by insulin resistance, hyperinsulinemia, hyperandrogenism and anovulation. Such factors are responsible for the increased miscarriage and infertility in women with PCOS. Administration of various insulin sensitizing drugs, such as metformin and t...
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عنوان ژورنال
دوره 7 شماره 3
صفحات 97- 97
تاریخ انتشار 2013-09-01
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