P-163: Evaluation of Ovarian Masses in Shahid Sadoughi and Mother Hospital during 2008-2012

Background: Ovarian cancer is the fifth most common cancer in woman and the fifth most frequent cause of cancer death. Ovarian cancers are usually asymptomatic until metastasized, patients have advanced disease at diagnosis in more than 2/3 of the cases. Totally 75-80 % of ovarian masses are benign. The strongest patient related risk factor for ovarian cancer is increasing age. The most ovarian masses in premenopausal are functional and ovarian cancer is rare (2% malignant, 20% benign, 72% functional) and in postmenopausal report of ovarian masses are: 10% malignant, 10% functional, 80% benign. Benign ovarian cysts characteristically are unilateral mobile, smooth but bilateral, solid and fixed masses should alert the clinician to a possible carcinoma. The size of masses shows the chance of malignancy, which usually smaller than 5 cm are benign. Materials and Methods: In this study, 659 ovarian masses evaluated, using the reports of pathology of patient with ovarian mass since Jan 2008 till Dec 2012 in mother and Shahid Sadoughi Hospitals. Questiannare is containing age, size ,essence, location, benign or malignant and type of pathology. The data was analyzed by spss (ver.15) and the following results were achieved. Results: Totally 95.1% (627 patients) of the masses were benign and 4.9% (32 patients) were malignant. Among the malignant type (32 patients), epithelial masses were the most common malignant tumor (53.1 %). Among the neoplastic types, (202 cases) 15.8% (32 cases) were malignant and (170 cases) 84.2% were benign. The mean age in malignant masses were 37.91 ± 18.52 (SD) and the mean age in benign masses were 31.33 ± 11.23 (SD) that it shows mean age in malignant masses is higher than benign masses. The mean size in malignant masses were 5.48 ± 4.67 (SD) cm that shows mean size in malignant masses is higher than benign masses. Among 659 ovarian masses 567 masses were cystic and 80 masses were mixed and 12 masses were solid that 41.7% of solid masses and 20% of mixed masses and 1.9% of cystic masses were malignant that it shows risk of malignancy in solid and mixed masses is higher than cystic masses. Conclusion: Ovarian masses are usually asymptomatic, in evaluation of them should be careful of all sings, because sometimes the malignant tumors are small or in young women.