P12: Progesterone Act as Neuroprotective in Traumatic Brain Injury
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منابع مشابه
p12: progesterone act as neuroprotective in traumatic brain injury
traumatic brain injury (tbi) is one of the leading causes of death in men under the age of 35 that mostly occurs due to the road accidents. current clinical treatments have not enough repair and prevention of secondary damage caused by cytotoxicity. progesterone, as a primary sex hormone, acts as neuroprotection in tbi and stroke. progesterone increases anti-oxidants and decreases inflammation ...
متن کاملProgesterone as a neuroprotective factor in traumatic and ischemic brain injury.
The search for a "magic bullet" drug targeting a single receptor for the treatment of stroke or traumatic brain injury (TBI) has failed thus far for a variety of reasons. The pathophysiology of ischemic brain injury and TBI involves a number of mechanisms leading to neuronal injury, including excitotoxicity, free radical damage, inflammation, necrosis, and apoptosis. Brain injury also triggers ...
متن کاملP7: Salutary Effects of Progesterone for Traumatic Brain Injury
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملNeuroprotective strategies for traumatic brain injury
Head trauma is a common event that often causes traumatic brain injury (TBI). Following the acute mechanical insult, TBI evolves over the ensuing minutes and days. Understanding the secondary factors that contribute to TBI might suggest therapeutic strategies to reduce the long-term consequences of brain trauma. To assess secondary factors that contribute to TBI, we studied a fluid percussion i...
متن کاملP86: Effect of Concomitant Use of Erythropoietin and Progesterone in Traumatic Brain Injury
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملProgesterone Provides the Pleiotropic Neuroprotective Effect on Traumatic Brain Injury Through the Nrf2/ARE Signaling Pathway
OBJECTIVE This study was to investigate the role of Nrf2/ARE signaling pathway in the pleiotropic neuroprotective effect of progesterone (PROG) on traumatic brain injury (TBI). METHODS The Nrf2-knockout (Nrf2-/-) and C57 mice were respectively subjected to a lateral cortical impact injury caused by a free-falling object and randomly divided into three groups: sham-operated, trauma, and trauma...
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عنوان ژورنال
دوره 3 شماره 4
صفحات 39- 39
تاریخ انتشار 2015-12
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