Paraoxonase Inhibition by Propranolol

نویسندگان

  • A Jahangiri
  • A Shafiee
  • H Jalalizadeh
  • M Mahmoudian
چکیده مقاله:

There are many evidences that human serum paraoxonase activity modifies plasma lipid profile and paraoxonase has an antiatherogenic property. Non-selective beta-blockers affect plasma lipid profile too, but they have atherogenic property when patients take these drugs in long term. In this study the effect of propranolol, a non-selective beta-blocker, on paraoxonase activity was investigated. Lineweaver-Burk and secondary plots were drawn and showed that propranolol is a mixed non-competitive inhibitor of paraoxonase.

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paraoxonase inhibition by propranolol

there are many evidences that human serum paraoxonase activity modifies plasma lipid profile and paraoxonase has an antiatherogenic property. non-selective beta-blockers affect plasma lipid profile too, but they have atherogenic property when patients take these drugs in long term. in this study the effect of propranolol, a non-selective beta-blocker, on paraoxonase activity was investigated. l...

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عنوان ژورنال

دوره Volume 3  شماره Number 3

صفحات  155- 158

تاریخ انتشار 2010-11-20

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