Preliminary pharmacological activity of the methanolic extract of Premna integrifolia barks in rats

نویسندگان

  • Al Mamun Department of Pharmacy, Rajshahi University, Rajshahi, Bangladesh
  • Badrul Alam Department of Pharmacy, Jahangirnagar University, Savar, Dhaka, Bangladesh
  • Efte Kharul Alam Department of Pharmacy, Atish Dipankar University of Science and Technology, Dhaka, Bangladesh
  • Hajera Khatun Department of Pharmacy, Southeast University, Dhaka, Bangladesh
  • Rajib Majumder Department of Pharmacy, Atish Dipankar University of Science and Technology, Dhaka, Bangladesh
  • Safkath Ibne Jami Department of Pharmacy, University of Asia Pacific, Dhaka, Bangladesh
چکیده مقاله:

Objective: Premna integrifolia Linn (Family: Verbenaceae) synonym of Premna serratifolia has tremendous medicinal value. Preliminary pharmacological studies were performed on the methanolic extract of Premna integrifolia (MEPI) bark to investigate neuropharmacological, analgesic, and anti-inflammatory activities. Materials and methods: Neuropharmacology study was done by open field and hole cross test whereas acetic acid writhing test and formalin induced pain was done for analgesic activity of MEPI. Carrageenan induced inflammatory model was considered for anti-inflammatory activity evaluation.   Results: A statistically significant (p

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preliminary pharmacological activity of the methanolic extract of premna integrifolia barks in rats

objective: premna integrifolia linn (family: verbenaceae) synonym of premna serratifolia has tremendous medicinal value. preliminary pharmacological studies were performed on the methanolic extract of premna integrifolia (mepi) bark to investigate neuropharmacological, analgesic, and anti-inflammatory activities. materials and methods: neuropharmacology study was done by open field and hole cro...

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عنوان ژورنال

دوره 4  شماره 3

صفحات  215- 224

تاریخ انتشار 2014-05-01

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