Relationship between serum levels of fetuin-A with apo-A1, apo-B100, body composition and insulin resistance in patients with type 2 diabetes
نویسندگان
چکیده مقاله:
Background :Some results exist on fetuin-A as marker for vascular disease in type 2diabetes. We examined the relationship between serum fetuin-A with some factors, in patients with type 2 diabetes mellitus (T2DM). Methods : From October 2012 to June 2013, a total of 131 T2DM patients were recruited and evaluated for various parameters including HOMA-IR, Apo-A1, Apo-B100, body fat percentage and waist circumference. Serum fetuin-A levels were measured by enzyme-linkedimmunosorbent assay (ELISA), and Serum glucose with a Cobas MIRA analyzer by enzymatic method. Apo-B100 and apo-A1 were measured by immunoturbidimetry with a Cobas MIRA analyzer. HOMA-IR was calculated by the following formula: [fasting insulin (uIU/mL) × fasting blood glucose (mmol/L)]/22.5. Results : The mean levels of HOMA-IR were significantly increased progressively across fetuin-A tertiles (pfor trend=0.04) in women but not men. Fetuin-A had just a significant positive correlation withApo- A1(r=0.22, p=0.02). Conclusion : This present study showed that levels of serum fetuin-A are significantly associated with insulin resistance in women with T2DM.
منابع مشابه
relationship between serum levels of fetuin-a with apo-a1, apo-b100, body composition and insulin resistance in patients with type 2 diabetes
background :some results exist on fetuin-a as marker for vascular disease in type 2diabetes. we examined the relationship between serum fetuin-a with some factors, in patients with type 2 diabetes mellitus (t2dm). methods : from october 2012 to june 2013, a total of 131 t2dm patients were recruited and evaluated for various parameters including homa-ir, apo-a1, apo-b100, body fat percentage a...
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عنوان ژورنال
دوره 28 شماره 1
صفحات 646- 652
تاریخ انتشار 2014-01
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