Sympathetic Skin Response in patients with major depressive disorders
نویسندگان
چکیده مقاله:
Introduction: Major depressive disorder (MDD) is one of the most prevalent diseases of psychiatry. There is evidence that suggests the autonomic nervous system plays a role in depression. Sympathetic Skin Response (SSR) is used to evaluate the autonomic system. Nerve Conduction Study (NCS) evaluates peripheral thick myelinated fibers. In SSR we evaluate thin unmyelinated fibers. The purpose of this study is evaluation of Sympathetic Skin Response in patients with MDD and control group. Materials and Methods: The case group include 20 patients (16 women and 4 men), suffering from MDD and control group include 19 subjects (12 women and 7 men) with mean age of 7.8431.65 and 6.99 32.10. Bilateral palmar and plantar latency and amplitude of SSR were recorded in response to Median and Tibial nerve electrical stimulation. Results: The data received from this study showed an increase in SSR amplitude in the case group compared to the controlled group in the upper extremities. In the lower extremities difference in SSR amplitude was not observed. There was no difference in SSR latencies between the case and control group. Conclusion: The results of this study may suggests that an increase in SSR amplitude in upper extremities can be useful in diagnosis and follow up of patients suffering from MDD and it indicates autonomic nervous system dysfunction in these people.
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عنوان ژورنال
دوره 24 شماره 6
صفحات 0- 0
تاریخ انتشار 2019-12
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