The assessment of function, histopathological changes, and oxidative stress in liver tissue due to ionizing and non-ionizing radiations
نویسندگان
چکیده مقاله:
Background: Compared to past decades, humans are exposed to rapidly increasing levels of radiofrequency electromagnetic radiations (RF-EMF). Despite numerous studies, the biological effects of human exposure to different levels of RF-EMF are not fully understood, yet. This study aimed to evaluate the bioeffects of exposure to "900/1800 MHz" and “2.4 GHz" RF-EMFs, and x-rays as well as their potential for inducing simple additive, adaptive, or synergistic effects. Methods: 120 Wistar rats were randomly divided into ten groups of 12 each. The rats were exposed to either sham, EMF, 10 cGy, and 8 Gy x-rays or a combination of these exposures. The levels of liver enzymes in serum samples by an auto-analyzer. Moreover, the histopathological changes and the levels of Malondialdehyde, Nitric oxide, ferric reducing antioxidant power, total thiols, and protein carbonyl assays were measured. Results: Among the markers of liver function, GGT was not associated with irradiation but, AST, ALT, and ALP showed some levels of association. Lipid peroxidation and protein carbonyl assays after 8 Gy irradiation were increased, but pre-exposure to RF-EMF could modulate their changes. At the cellular level, the frequency of lobular inflammation was associated with our intervention types. Conclusions: the exposure to both ionizing and non-ionizing radiations could alter some liver function tests. A short term pre-exposure to RF-EMF before exposure to an 8 Gy challenging dose of x-rays caused the alterations in oxidative stress markers and liver function tests, which indicate the possible involvement of oxidative stress in the process of adaptive response.
منابع مشابه
patterns and variations in native and non-native interlanguage pragmatic rating: effects of rater training, intercultural proficiency, and self-assessment
although there are studies on pragmatic assessment, to date, literature has been almost silent about native and non-native english raters’ criteria for the assessment of efl learners’ pragmatic performance. focusing on this topic, this study pursued four purposes. the first one was to find criteria for rating the speech acts of apology and refusal in l2 by native and non-native english teachers...
15 صفحه اولMedical knowledge on ionizing radiations
I have read with great concern the article written by Borém et al. (1) – " The knowledge about diagnostic imaging methods among primary care and medical emergency physicians " –, published by Radiologia Brasileira in December/2013. The presented results show in a hard-hitting way that physicians are educated even without an appropriate idea about what is ionizing radiation, radiological imaging...
متن کاملthe role of russia in transmission of energy from central asia and caucuses to european union
پس ازفروپاشی شوروی،رشد منابع نفت و گاز، آسیای میانه و قفقاز را در یک بازی ژئوپلتیکی انرژی قرار داده است. با در نظر گرفتن این منابع هیدروکربنی، این منطقه به یک میدانجنگ و رقابت تجاری برای بازی های ژئوپلتیکی قدرت های بزرگ جهانی تبدیل شده است. روسیه منطقه را به عنوان حیات خلوت خود تلقی نموده و علاقمند به حفظ حضورش می باشد تا همانند گذشته گاز طبیعی را به وسیله خط لوله مرکزی دریافت و به عنوان یک واس...
15 صفحه اولRadiation Effects and Damage 1. Ionizing Radiations
The detrimental consequences of radiation are referred to as radiation damage. To understand the effects of radiation, one must first be familiar with the radiations and their interaction mechanisms. Further, the fundamental characteristics of the material(s) being irradiated must also be understood. A brief summary of the characteristics of radiation is first presented below. This is followed ...
متن کاملcontribution of setting to the study of characters and the main idea in e. brontes: wuthering heights and t. hardys: return of the native.
this thesis aims to adduce an unmitigated and comprehensive explication concerning the relationship of three significant elements of fiction: setting, chracter and theme. my research is basically placed on two outstanding novels of the 19th century: emily brontes wuthering heights and thomas hardys return of the native. my endeavour lies in studying the correlation among the three above-mention...
15 صفحه اولمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 11 شماره 3
صفحات 12- 0
تاریخ انتشار 2020-05
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023