Amirhossein Sahebkar

Metabolic Research Centre, Royal Perth Hospital, School of Medicine and Pharmacology, University of Western Australia, Perth, Australia

[ 1 ] - Evaluation of Total Phenolic Content and Antioxidant Activity in Ten Selected Mahaleb (Prunus mahaleb L.) Genotypes

Mahaleb (Prunus mahaleb L.) is an important rootstock for P. avium and P. cerasus cultivars. The present study has compared the phenolic contents and antioxidant activity of the methanolic extracts of the barks, leaves and fruits of ten selected mahaleb genotypes. The total phenolic content (5.11-131.77 mg GA g-1) in barks and the total flavonoid (54.06-180.6 mg QE g-1) and proanthocyanidin (8....

[ 2 ] - درمان سرطان بر پایه داروهای متصل به آنتی‌بادی

سابقه و هدف: در دهه های اخیر استفاده از داروهای کونژوگه شده با آنتی بادی، امیدهای بسیاری را در زمینه درمان سرطان بوجود آورده است. در این نوع درمان از یک آنتی بادی تک دودمانی بر علیه یک آنتی ژن اختصاصی سرطان استفاده می شود که داروی سیتوتوکسیک به وسیله یک لینکر به آن متصل شده است. به این سیستم دارو رسانی هوشمند آنتی بادی مسلح نیز اطلاق می­شود. در این مطالعه مروری به بررسی این عوامل پرداخته و فاکت...

[ 3 ] - Prevalence of Antibiotic Resistance of Haemophilus Influenzae in Iran- A Meta-Analysis

Introduction: Based on the World Health Organization reports, infections caused by ampicillin-resistant Haemophilus influenzae strains are a major threat to public health and need urgent therapy with new antibiotics. Given the lack of a previous comprehensive study on the prevalence of the antibiotic resistance of H. influenzae in Iran, this systematic review and meta-analysis was perform...

[ 4 ] - Diversity of Toll-like Receptor Genes and Helicobacter Pylori Infections: A Meta-Analysis Study

Background and Aims: Several studies have shown that host genetic factors can be associated with the risk of developing Helicobacter pylori infections. Therefore, we evaluated the most prevalent toll-like receptors (TLRs) polymorphisms in Helicobacter pylori positive subjects and their possible role in susceptibility to Helicobacter pylori infections. Materials and Methods: Using related keywo...

[ 5 ] - A Review of the Possible Effects of Curcumin in the Treatment of COVID-19

COVID-19, which is caused by the SARS-Cov-2, begins with early symptoms of fever, cough, shortness of breath, myalgia, and fatigue, affecting the lungs with pneumonia and causing acute respiratory distress syndrome (ARDS). Also, the onset of the disease may with rapid progression, lead to organ dysfunction, such as acute kidney or liver damage, and even death in severe cases. Many scientific ef...