Abdolvahab Moradi

Department of Medical Virology, Golestan University of Medical Sciences, Gorgan, Iran

[ 1 ] - Detection of Human Papillomavirus in Osophageal Squamous Cell Carcinoma samples in Mazandaran Province, Iran

We examined 170 formalin-fixed paraffin-embedded samples from esophageal squamous cell carcinoma patients. All subjects live in Mazandaran province, a region with high incidence rate of esophageal cancer and have become known as the “Asian Esophageal Cancer Belt”. Samples were tested for HPV-DNA by MY09/11 and Gp5+/6+ general primers using nested PCR. Of the 170 ESCC samples, 86 (50.6%) were ma...

[ 2 ] - میزان پاسخ‌دهی به واکسیناسیون هپاتیت B در کودکان کمتر از یک‌سال شهر گرگان

زمینه و هدف : واکسیناسیون یکی از موثرترین روش‌های پیشگیری از بیماری هپاتیت B در سرتاسر دنیا می‌باشد. این مطالعه به منظور بررسی میزان پاسخ‌دهی به واکسیناسیون هپاتیتB در کودکان کمتر از یک‌سال در شهر گرگان انجام گردید. روش بررسی: این مطالعه توصیفی- مقطعی روی 215کودک 7 تا 12 ماهه (3/55 درصد پسر و 7/46 درصد دختر) شهر گرگان که سه‌نوبت واکسیناسیون بر علیه هپاتیت B را کامل دریافت کرده بودند، در سال ...

[ 3 ] - Evaluation of anti-hepatitis E virus antibody among hemodialysis patients in Gorgan, north of Iran

Background and Aims: Hepatitis E virus is a public health concern and about a third of people in the world live in endemic areas. Although HEV is believed to be transmitted by fecal-oral routes between humans in low sanitary conditions, but evidence of transmission have been reported in hemodialysis (HD) patients. Materials and Methods: Aim of present study was to determine the prevalence of a...

[ 4 ] - HHV-6 DNA and Antibody Detection in Plasma and PBMC of Multiple Sclerosis Patients in North of Iran

Abstract Background and Aims: Multiple sclerosis (MS) is defined by the presence of inflammatory demyelinating plaques in the central nervous system (CNS). It has been indicated that human herpes virus 6 (HHV-6) may play role in pathogenesis of MS. The aim of this study was to determine the presence of HHV-6 DNA and anti HHV-6 IgG in MS patients and controls. Materials and Methods: Bloo...

[ 5 ] - Mutations in the Basal Core Promoter and Precore/Core Regions of Hepatitis B Virus in Patients Co-Infected With Human Immunodeficiency Virus

ABSTRACT          Background and objectives: Globally, about one third of the population has been infected with Hepatitis B virus (HBV) and more than 400 million people have become chronically infected. Nearly, 20-25% of all carriers develop serious liver diseases such as cirrhosis, chronic hepatitis and hepatocellular carcinoma (HCC). According to t...

[ 6 ] - Drug-Resistant HIV-1 RT Gene Mutations in Patients under Treatment with Antiretroviral Drugs (HAART) in Iran

Abstract Background and Objective: Highly Active Antiretroviral Therapy (HAART) can effectively prevent the progression of HIV-1 replication and increase life expectancy. There are numerous causes of treatment failure and the leading one is drug resistance. Thus, we aimed to determine the HIV RT gene drug resistance mutations in patients treated with antiretroviral medications. Material...

[ 7 ] - Drug- Resistance- Associated Mutations and HIV Sub-Type Determination in Drug-Naïve and HIV-Positive Patients under Treatment with Antiretroviral Drugs

Abstract Background and Objective: Resistance to antiretroviral agents is a significant concern in clinical management of HIV-infected individuals. Resistance is the result of mutations that develops in the viral protein targeted by antiretroviral agents. Material and Methods: In this cross-sectional study, the blood samples of 40 HIV-positive patients were collected. Twenty of them were d...

[ 8 ] - HIV false positive results and Flu vaccination

Abstract False positive results are the major problem influencing interpretation of Clinical Laboratory test. They are originated mostly in the other diseases, technical errors and the recent vaccination. The problem has been presented since 1991 is positive HIV test after influenza Vaccination (1). The False positive has been reported in Cases using Eliza, one of The most common test to screen...

[ 9 ] - Survey of HTLV-1 Antibody Among Thalassemic Patients in Gorgan

Abstract Background and objectives: HTLV-1 virus belongs to the retrovirus and infection with this virus mostly is seen among people having more than one time blood transfusion. Because of requiring repeated blood transfusions, thalassemic patients are considered to be high risk subjects in this regard. Thus, this study was carried out to indicate the frequency of HTLV-1 infection among the tha...