Mohammad Karimian
Anatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran
[ 1 ] - Lipoprotein lipase gene polymorphisms as risk factors for stroke: a computational and meta-analysis
Objective(s): Stroke is the most common neurological disorder and genetic susceptibility has an important role in its etiology. Polymorphism in several genes such as lipoprotein lipase (LPL) is propounded as a risk for stroke. This meta-analysis investigated the association of rs285 and rs320 LPL polymorphism with stroke risk. Materials and Methods: We searched PubMed, Clarivate Analytics Web o...
[ 2 ] - ارتباط پلی‌مورفیسم های c.*49T>C و c.-932 G>A ژن CYBA با بیماری عروق کرونر: یک مطالعه مورد- شاهدی در جمعیت مردم کاشان
زمینه: ژن (Cytochrome B-245 Alpha Chain; p22phox) CYBA، کد کننده زیر واحد اصلی آنزیم NADH/NADPH- اکسیداز است. این آنزیم در سلول‌های عضلات صاف دیواره رگ‌ها بیان می‌شود، که گونه‌های فعال اکسیژن را تولید می‌کنند. از سوی دیگر استرس اکسیداتیو در پاتوژنز بیماری عروق کرونر (Coronary Artery Disease; CAD) نقش اساسی دارد. هدف از این مطالعه بررسی ارتباط پلی‌مورفیسم‌های (c.*49T>C) rs7195830 و (c.-930G>A)rs...
[ 3 ] - Association of Some High-Risk Mucosal Types of Human Papillomavirus with Cutaneous Squamous Cell Carcinoma in an Iranian Population
Background & Objective: Squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer that may be caused by Human papillomavirus (HPV), especially in immunosuppressed patients. However, the role of the mucosal types of HPV in SCC patients with normal immunity has not been extensively confirmed. The aim of this study was to investigate the association...
[ 4 ] - IL-1ɑ C376A Transversion Variant and Risk of Idiopathic Male Infertility in Iranian Men: A Genetic Association Study
Objective IL-1α produces by sertoli cells and considered as a growth factor for spermatogonia. In this study we investigated the association of C376A polymorphism in IL-1α gene with male infertility in men referring to Kashan IVF center which followed by an in silico approach. MaterialsAndMethods In a case-control study, 2 ml blood was collected from 230 fertile and 230 infertile men. After DNA...
نویسندگان همکار