Maryam Baazm

Department of Anatomy, School of Medicine, Arak University of Medical Sciences, Arak, Iran

[ 1 ] - Resveratrol decreases apoptosis and NLRP3 complex expressions in experimental varicocele rat model

Objective(s): Varicocele is an abnormal dilation in the testicular vein, which can cause hypoxia, reactive oxygen species accumulation, elevation in testicular temperature, and promote apoptosis and increase proinflammatory cytokine production. According to the varicocele pathophysiology, it is possible that a group of cytosolic receptors called nucleotide oligomerization domain (NOD)-like rece...

[ 2 ] - Heterologous expression of a truncated form of human recombinant vascular endothelial growth factor-A and its biological activity in wound healing

Objective(s): Vascular endothelial growth factor (VEGF) is one of the most effective proteins in angiogenesis, mesenchymal stem cells (MSCs) differentiation and wound healing. These abilities are therapeutic potential of VEGF in diabetic retinopathy, nephropathy and other tissue damage circumstances. In this study, recombinant VEGF was produced in Escherichia coli (E. coli) system and then biol...

[ 3 ] - طراحی کاست ژنی، کلونینگ و بیان پلی‌پپتید شبه الاستین نوترکیب به منظور تولید بیومتریال کاربردی در مهندسی بافت

سابقه و هدف: پلی‌پپتید شبه الاستین (Elastin-like polypeptide, ELP) بیومتریال مصنوعی برگرفته از توالی پنتاپپتید  Val-Pro-Gly-Xaa-Gly (VPGXG) الاستین ماتریکس خارج سلولی (ECM) است. پلیمرهای پروتئینی که از واحدهای تکراری اسیدهای آمینه طبیعی و غیرطبیعی پدید می‌آیند، به‌عنوان رده‌ای جدید از بیومواد شناخته می‌شوند. ویژگی‌های منحصر به فرد ELP همانند تولید بر پایه بیان ژنتیکی در انواع رده‌های میزبانی (...

[ 4 ] - Case Report: A Rare Variation in Origin of Common Interosseous Artery: A Review of Anatomical Studies and Case Report

An unusual origin of the common interosseous artery is reported in the paper. During educational dissection of a 37-year-old male, a rare variation in the origin of common interosseous artery of the right upper limb was observed. The common interosseous artery directly separated from radial artery. The right anterior interosseous artery is continued from common interosseous artery. Anterior and...

[ 5 ] - Assessment of In Vitro-Derived Germ Cells Contribution in Oogenesis in Female Mice Ovaries

Introduction: Contrary to a common belief, most mammalian females lose the ability of Germ Cell (GC) renewal and oogenesis during fetal life. Although, it has been claimed that germ line stem cells preserve oogenesis in postnatal mouse ovaries, that postnatal oogenesis keeps producing functional and sufficient GCs in the case of infertility (caused by different reasons) is doubtful. On the othe...

[ 6 ] - Presence of The NLRP3 Inflammasome Components in Semen of Varicocele Patients

Background: Varicocele is a common cause of male infertility with multifactorial etiology. Inflammation is a characteristic pathological event that occurs in the testis tissue following the varicocele. The aim of this study was to investigate expression of nod-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome components and cytokines in semen of varicocele and control subject...

[ 7 ] - Effect of Resistance and Endurance Trainings on Nrf2/Keap1 Signaling Pathway in Testicular Tissue of Type 2 Diabetic Rats

Background and purpose: The antioxidant Nrf2/Keap1 pathway prevents cellular damages against oxidative stress and this pathway is disrupted following diabetes. The aim of this study was to investigate the effect of endurance and resistance training on antioxidant Nrf2/Keap1 pathway in testicular tissue of diabetic rats. Materials and methods: In this experimental research, 48 male Wistar rats ...

[ 8 ] - Correction to: Effect of Resistance and Endurance Trainings on Nrf2/Keap1 Signaling Pathway in Testicular Tissue of Type 2 Diabetic Rats

Correction to: Effect of Resistance and Endurance Trainings on Nrf2/Keap1 Signaling Pathway in Testicular Tissue of Type 2 Diabetic Rats Zahra Nadi1, Yusef Abbasi2, Farideh Jalali Mashayekhi3, Mohammad Bayat2, Parvindokht Bayat4, Maryam Baazm5 1 MSc in Anatomy, School of Medicine, Arak University of Medical Sciences, Arak, Iran 2 Assistant Professor, Department of Anatomy, Scho...