Nourieh Sharifi

Department of Pathology, Mashhad University of Medical Sciences, Mashhad, Iran

[ 1 ] - Calretinin Immunohistochemistery: An Aid in the Diagnosis of Hirschsprung’s Disease

Objective(s) Definite diagnosis of Hirschsprung’s disease (HD) is based on histopathological study, but there are limitations associated with standard histology and histochemistry in this regard. The aim of this study was to investigate calretinin immunostaining patterns in both ganglionic and aganglionic HD intestinal specimens and to compare them with control specimens. Materials and Method...

[ 2 ] - Failure to Demonstrate the Role of High Risk Human Papilloma Virus in Epithelial Ovarian Cancer

Background and Aims: Ovarian cancer is one of most common causes of cancer related women's mortalities. Human papilloma virus is a known factor concerning cervical cancer but its role in causing ovarian cancer is not yet verified. A few studies also identified HPV DNA in ovarian carcinoma tissues. However, some studies did not detect HPV DNA in ovarian carcinoma tissues. In this articl...

[ 3 ] - Placental Site Trophoblastic Tumor: Clinical and Pathological Report of Two Cases

  Placental site trophoblastic tumor (PSTT) is the rare variant of gestational trophoblastic diseases (GTD), which differs histologically and immunologically from GTD. Diagnosis of PSTT is often difficult and delayed. In most cases, diagnosis is not possible until the surgery is performed. The most therapeutic choice is hysterectomy and it is usually successful. Here we report two cases of PST...

[ 4 ] - An Immunohistochemical Study Of P63 Protein Expression In Meningioma

  Background and Objective: Histological grading has prognostic and therapeutic implications in meningioma. However, histological criteria are sometimes not fulfilled to predict the biological behavior of meningiomas. P63 gene is a novel P53 family member, known as tumor suppressor factor, with multiple isoforms and shows high expression in many normal and neoplastic human tissues. In this stu...

[ 5 ] - Cytodiagnosis of Cutaneous Basal and Squamous Cell Carcinoma

Background and Objective: Cutaneous cytology is the study of scraping or smears obtained from skin lesions. Although not commonly employed, cutaneous cytology has been a useful tool for clinicians due to simplified procedures and high sensitivity and specificity of presurgical clinical diagnosis of commo...

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