Zohreh Babaloo
Department of Immunology, Faculty of Medicine | Neuroscience Research Center | Immunology Unit, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
[ 1 ] - Increased IL-17A but Decreased IL-27 Serum Levels in Patients with Multiple Sclerosis
Background: Effector CD4+ T cell subsets play an important role in Multiple Sclerosis (MS). Interleukin-27 (IL-27) suppresses Th (Th1, Th2 and Th17) cells and dampens autoimmunity and tissue inflammation by promoting the generation of Type 1 regulatory T cells (Tr1). Objective: To identify the relative levels of IL-27 and IL-17A in MS disease. Method: In a case-control study, venous blood was c...
[ 2 ] - Elevated Levels of Interleukin-23 in Sera of Patients with Pemphigus Vulgaris
Background: Pemphigus vulgaris, a chronic mucocutaneous disease, is the most prevalent type of pemphigus which manifests with development of bullae and erosions on skin and mucosal membranes. Objectives: To investigate the potential role of IL-23 in pemphigus vulgaris. Methods: In this study, 30 patients with pemphigus vulgaris and 30 healthy individuals were selected according to inclusion and...
[ 3 ] - Interleukin-17A and Interleukin-17F mRNA Expressions in Peripheral Blood Mononuclear Cells of Patients with Multiple Sclerosis
Bakground: Multiple sclerosis (MS) is a CD4+ T cell-mediated autoimmune disease affecting the central nervous system (CNS). It was previously believed that Th1 cells were pathogenic T cells in experimental autoimmune encephalomyelitis (EAE). However, the functional role of Th1 cells in EAE has been reconsidered upon the discovery of IL-17- producing T cells which are consider as dominant effect...
[ 4 ] - Effects of fasting on the immune system function and its positive effects on the chemotherapy of various types of cancer
Fasting is one of the most basic religions in Islam. The body considers fasting as a stress and tries to cope with it through a path called self-regulating stress. The effects of fasting on various diseases and different physiological conditions have been evaluated and its positive effects have been shown in many diseases. The effects of fasting on the immune system of healthy people in general...
[ 5 ] - Investigation of Chitinase3like-1 (Chiti3L1) Gene Polymorphism (rs4950928) with Susceptibility to Allergic Asthma in Iranian Northwestern Azeri Population
Background: In addition to cellular and molecular mechanisms involved in the pathogenesis of asthma, mounting evidences demonstrate that single nucleotide polymorphisms (SNPs) in asthma relevant genes have a role in conferring susceptibility to the disease. CHI3L1 is secreted from macrophages, neutrophils, and airway epithelial cells through an IL-13 related mechanism and contributes to tissue ...
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