Dariush Shanehbandi

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

[ 1 ] - Effects of CD133 Silencing on Survival and Migration of HT-29 Colorectal Cancer Cells

Background: Colorectal cancer (CRC) is attributed as one of the most common malignancies worldwide. CD133 molecule, as a pentaspan transmembrane glycoprotein, confers stem cell-related characteristics, including self-renewal and multi-directional differentiation capability. CD133 plays important roles in the progression of CRC by conferring apoptotic resistance and migration ab...

[ 2 ] - Investigation of Chitinase3like-1 (Chiti3L1) Gene Polymorphism (rs4950928) with Susceptibility to Allergic Asthma in Iranian Northwestern Azeri Population

Background: In addition to cellular and molecular mechanisms involved in the pathogenesis of asthma, mounting evidences demonstrate that single nucleotide polymorphisms (SNPs) in asthma relevant genes have a role in conferring susceptibility to the disease. CHI3L1 is secreted from macrophages, neutrophils, and airway epithelial cells through an IL-13 related mechanism and contributes to tissue ...