Karim Khoshgard

Department of Medical Physics& Medical Engineering, Kermanshah University of Medical Sciences, Kermanshah, Iran

[ 1 ] - Determination of Radionuclide Concentrations in Tea Samples Cultivated in Guilan Province, Iran

Introduction Foodstuffs are known to contain natural and artificial radionuclides. Determination of radionuclide concentration is of great significance for the protection of human health. The main objective of the present study was the quantification of radionuclides in tea samples, cultivated in Guilan Province in North of Iran. Materials and Methods The activity concentrations of 226Ra, 232Th...

[ 2 ] - پیش بینی آسیب بافت ریه از طریق بررسی پارامترهای بالینی و دزیمتریکی در بیماران مبتلا به سرطان پستان

Background and purpose: Breast cancer is the most common type of cancer among women. In radiation therapy for breast cancer it is important to prevent damage to normal tissues particularly to lung tissue. In this study, we investigated the incidence of damage in patients with breast cancer by clinical and dosimetric parameters to identify the predictive factors. Materials and methods: An exp...

[ 3 ] - بررسی انکسار پرتوهای فراصوت در هایفوتراپی و بهینه سازی عمق کانونی مبدل فراصوت جهت افزایش دقت درمان

Background and purpose: Nowadays High-intensity focused ultrasound (HIFU) as non-ionizing radiation is used for cancer treatment. Ultrasound beams when crossing the border of two environments are refracted causing decrease in the beam focusing within a tumor. Also, it may induce damage to normal tissues. In this study, we evaluated the focal depth shift induced by ultrasonic beam refraction. ...

[ 4 ] - بررسی اثر حساس کنندگی پرتویی نانوذرات اکسید آهن با پوشش دکستران بر روی سلول های سرطانی دهانه رحم تحت تابش با باریکه های فوتونی MV6

Background and purpose: The use of nanotechnology is increasing in different fields of medical sciences including diagnosis and treatment. Metal nanoparticles such as Iron nanoparticles are proposed as novel radiation-sensitizing agents in enhancing the efficiency of radiotherapy because they have a large number of atoms. This study aimed at investigating the radiosensitivity effect of dextran-...

[ 5 ] - The measurement of solar ultraviolet radiation in Kermanshah city over a one-year period from 2015 to 2016

ABSTRACT Background: Ultraviolet radiation is present in sunlight. If ultraviolet radiation exceeds the limit, it can cause detrimental effects on human health such as skin cancer and cataract. Materials and Methods: In this descriptive cross-sectional study, the level of solar ultraviolet radiation type A (UVA) were measured using UV LOG HAND HELD in Kermanshah city. The intensity of ultravio...

[ 6 ] - The Cytotoxicity of Dextran-coated Iron Oxide Nanoparticles on Hela and MCF-7 Cancerous Cell Lines

Background: Recently, iron oxide nanoparticles have attracted attention in various diagnosis and treatment fields. The aim of the present study was to investigate the cytotoxicity of various concentrations and incubation times of dextran-coated iron oxide nanoparticles (DIONPs) on HeLa and MCF-7 cancerous cell lines. Methods: This in-vitro study was conducted at Pharmaceutical Sciences Researc...

[ 7 ] - Natural Radioactivity Level of 226Ra, 232Th, and 40K Radionuclides in Drinking Water of Residential Areas in Kermanshah Province, Iran using Gamma Spectroscopy

Introduction: Human has always been exposed to background ionizing radiation. Interaction between ionizing radiation and the biological system can lead to changes in cells or tissues inducing diseases, such as cancer. With this background in mind, this experimental study aimed to evaluate the specific activity of water radionuclides in Kermanshah province, western region of Iran. Material and M...

[ 8 ] - Radiation dose of Pediatrics in a general hospital in comparison to a pediatrics hospital

Introduction: Increasing CT scan application increased the cancer risk in pediatrics in recent decays. Imaging centers approach for diagnosis of disease cause to different radiation dose to patients.  Because  of  rapid  pediatrics  body  growth,  the  most  important  challenge to determining the radiation dose is wide variations of size in different ages. Thus, we used Size...

[ 9 ] - Evaluation of methods of co-segmentation on PET/CT images of lung tumor: simulation study

Introduction: Lung cancer is one of the most common causes of cancer-related deaths worldwide. Nowadays PET/CT plays an essential role in radiotherapy planning specially for lung tumors as it provides anatomical and functional information simultaneously that is effective in accurate tumor delineation. The optimal segmentation method has not been introduced yet, however several ...

[ 10 ] - A study on the prevalence of hearing loss after head and neckradiotherapy with three-dimensionalconformal radiotherapy (3D-CRT)

Introduction:Radiotherapy (RT) plays an important role in treatment of head and neck cancers. In almost 75% of patients with head and neck cancers, RT as the main treatment method is used in order to radical or palliative treatment. Hearing loss is one of the side effects of RT for patients whose inner ear is included in radiation field. The aim of this study was to evaluate th...

[ 11 ] - Cytotoxicity of 5-ALA-conjugated bismuth oxidenanoparticles on KB cell line

Introduction: In recent years, bismuth-based nanomaterials have been widely used in medical researches as imaging, drug delivery and x-ray radiosensitizing agents. Due to their anti-microbial effects against Helicobacter pylori (HP), bismuth colloidal compounds are used to treat various types of diseases such as chronic gastritis. Despite their advantages, bismuth-based compoun...

[ 12 ] - Assessment of polymer composite reinforced with nanomaterial against ionizing radiation

Introduction: Unwanted exposure of ionizing radiation may result in carcinogenesis, cell mutations, and organ failure. High-atomic number elements such as lead, tungsten, bismuth have been traditionally used for radiation protection. Theoretical and practical studies have shown that a variety of shielding materials e.g. polymer composites (PCs) can be used for attenuation of th...

[ 13 ] - Consider potential of gold nanoparticles with proton therapy compared with KV and MEV X-ray therapy.

Introduction: Many study shown the effectiveness dose enhancement with gold nanoparticles (GNPs), especially with low-energy x-rays. Recently, proton beam radiation therapy (PBRT) has attention as a treatment for tumors. The advantage in PBRT, which releases high dose at the controllable Bragg peak position that localized for Au target and the released dose increased in depth....

[ 14 ] - Brain Activity Map Extraction from Multiple Sclerosis Patients Using Resting-State fMRI Data Based on Amplitude of Low Frequency Fluctuations and Regional Homogeneity Analysis

Introduction: Multiple Sclerosis (MS) is the most common non-traumatic neurological diseases of young adults. MS often reported during ages 20-62. MS affects the various anatomical parts of the central nervous system. Up to 65% of multiple sclerosis patients MS patients suffer from various problems, such as fatigue, depression, pain and sleep disorders. Unlike MRI, that only sh...

[ 15 ] - Brain Activity Map Extraction of Neuromyelitis Optica Patients Using Resting-State fMRI Data Based on Amplitude of Low Frequency Fluctuations and Regional Homogeneity Analysis

Introduction: Neuromyelitis Optica (NMO) is a rare inflammatory disease of the central nervous system which generally affecting the spinal cord and optic nerve. Damage to the optic nerve can result in the patient's dim vision or even blindness, while the spinal cord damage may lead to sensory and motor paralysis and the weakness of the lower limbs in the patient. Magnetic Reson...

[ 16 ] - Investigating of relationship between the parameters related to the treatment planning and the biological parameters in radiation induced pneumonitis in breast cancer patients

Introduction: The purpose in this study is to analyze of DVH parameters as predictors of radiation pneumonitis and investigation on the relationship between dosimetric and clinical parameters based on PFTs as response in NTCP model and therefore achieve to lung dose- response relation in breast cancer patients. Prescribed dose to treatment volumes was 50 Gy in 2.0 Gy/fractions ...

[ 17 ] - Positional changes in parotid glands during head and neck radiation therapy

Introduction: Xerostomia is the most common complication due to radiation–induced damage to salivary glands in head and neck cancer radiotherapy and it reduces quality of life. Parotid glands are main glands which they are account for secretion of stimulated saliva. Studies have demonstrated that mean tolerance parotid’s radiation dose under 26-30 Gy result in an increase in t...

[ 18 ] - Review of mechanisms and recent advances in cancer photo thermal therapy

Abstract. Cancer is a major health problem all over the world. Photo thermal therapy (PTT) is a non-invasive method in cancer treatment. In PTT, the laser light usually in near-infra red region is absorbed and converted to heat in the cancerous tissue. The temperature above 40 ° C in PTT can induce some effects including irreversible damage to proteins, changes in enzyme struc...

[ 19 ] - An Investigation to Determine an Optimum Protective Garment Material in Nuclear Medicine

Aim: The aim of this study is to find an optimum material to protect garment for protection against 99Tcm radionuclide.Materials and Methods: Monte Carlo simulation code was applied to investigate radiation attenuation of 13 shielding materials including: Ba, gray Sn, white Sn, Sb, Bi, Bi2O3, BaSO4, Sn/W, Sb/W, Pb and W with thicknesses of 0.5 and 1 mm to determine an optimum protective garment...