Vahid Reza Dabbagh Kakhki
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
[ 1 ] - Abnormal cerebral blood flow in methamphetamine abusers assessed by brain perfusion single emission computed tomography
Introduction:Amphetamines are central nervous system (CNS) stimulant substances and amphetamine abuse is considered a growing problem in our country. Previous studies revealed destructive effects of amphetamines on metabolism, perfusion and structure of brain. The aim of current study was evaluating regional cerebral blood flow (rCBF) disturbances in methamphetamine (MA) abuser...
[ 2 ] - Nicorandil effect on myocardial perfusion in patients with slow coronary flow phenomenon assessment by gated myocardial perfusion SPECT
Introduction:Patients with the coronary slow flow phenomenon (SCF) frequently experience angina episodes. The purpose of this study was to determine efficacy of nicorandil in myocardial perfusion in patients with SCF. Methods: Twenty patients (50.85 ± 12.96 y) with SCF were studied. We evaluate coronary slow flow according to protracted thrombolysis in m...
[ 3 ] - Can gallbladder ejection fraction measured by fatty meal cholescitigraphy diagnose chronic cholecystitis?
Introduction: Despite presence of a body of evidence in support of high accuracy of cholecystokinin cholescintigraphy (CCK-CS) , for diagnosis of chronic cholecystitis(CC) , some authors have claimed that gallbladder ejection fraction (GBEF) has poor predictive diagnostic values. The purpose of this study was to determine if there is any difference in GBEF between...
[ 4 ] - Echocardiographic left ventricular functional changes in acute hypothyroidism vs. subclinical hyperthyroidism in patients with differentiated thyroid carcinoma
Introduction: In order to assess echocardiographic left ventricular functional indices in patients with differentiated thyroid carcinoma (DTC), after L-T4 withdrawal (short-term overt hypothyroidism) and during TSH suppressive therapy, we have evaluated cardiac hemodynamics in a single cohort study. Methods: 24 patients with DTC were studied in two phases: 1: at least 4 weeks after L-T4 withd...
[ 5 ] - Effect of evidence based medicine training in the quality of journal clubs: A road to evidence based journal clubs
Introduction: Journal clubs play an important role in teaching Evidence Based Medicine (EBM). Evidence based journal clubs focus on real problems of the group, and set a minimum level of evidence for articles to be presented, and in the end a clinical bottom line is set to be used in the daily clinical practice. In this article, we have explained our experience in r...
[ 6 ] - Sentinel lymph node biopsy in melanoma patients: An experience with Tc-99m antimony sulfide colloid
Introduction: Sentinel lymph node biopsy is the standard procedure for lymph node staging in intermediate thickness melanoma. In Iran, this procedure has not been addressed sufficiently. In this study, we report our experience in this area. Methods: Ten consecutive patients with intermediate thickness melanoma where included in our study. 1.5 mCi of Tc-99m antimony...
[ 7 ] - Sensitivity of gallium scintigraphy for evaluation of recurrent lymphoma: Comparison of planar and SPECT imaging
Introduction: Although PET scanning using F-18[FDG] is considered the superior radiotracer for tumnor imaging, Gallium-67 is still in use for some malignancies such as lymphoma and hepatoma. One of the strategies to improve the diagnostic accuracy of Gallium is to perform SPECT which is reported to be more sensitive compared to planar imaging. In this study we compa...
[ 8 ] - Incidental change in photopeak during a dynamic renal scan
Abstract is NOT available
[ 9 ] - Minimally invasive radio-guided surgery for hyperparathyroidism: an experience with Tc-99m Sestamibi
Introduction: Radio-guided parathyroid surgery along with other minimally invasive surgeries constitutes the main surgical treatment procedures for different kinds of hyperparathyroidism. In this article we have reported our experience of radio-guided parathyroid surgery using Tc-99m sestamibi. Methods: Ten patients with hyperparathyroidism included in our study. ...
[ 10 ] - The need for skin pen marking for sentinel lymph node biopsy: A comparative study
Introduction: There is a consensus in the literature that sentinel lymph node biopsy is the standard procedure for axillary staging in early stage (I and II) breast cancer patients. Usually during lymphoscintigraphy, the location of the sentinel lymph node is marked on the skin by an indelible ink. In this study we evaluated this issue in our patients. Methods: 40 ...
[ 11 ] - Diffuse bilateral breast uptake on the myocardial perfusion SPECT of a nursing female
Bilateral diffuse intense breast uptake was noted in a 40 year old female who was evaluated with Tc-99m sestamibi (MIBI) myocardial perfusion scan for possible ischemia. She was breast feeding her 1.5 year old child. The intense uptake in the breasts was superimposed on the apical and anteroapical regions of the myocardium and caused interpretation problem. We recom...
[ 12 ] - Delayed imaging for detection of Meckel's diverticulum in Tc-99m pertechnetate scintigraphy
Tc-99m pertechnetate scintigraphy is the modality of choice for diagnosis of Meckel's diverticulum. Interpretation of Meckel's scan identifies a focal area of radiopharmaceutical uptake in the anterior abdomen similar to normal gastric mucosa. The activity must be of the same pattern and intensity as gastric uptake. We present a 13-year-old patient with gastrointest...
[ 13 ] - Normal values of left ventricular functional indices in gated 99mTc-MIBI myocardial perfusion SPECT
Introduction: Although left ventricular(LV) function parameters measured by gated myocardial perfusion SPECT (GSPECT) have been validated, experimental data have revealed that the calculated the LV function parameters using GSPECT are affected by patient populations as well as particular acquisition and processing conditions. We tried to determine the normal values ...
[ 14 ] - Persistent sub-diaphragmatic activity on the myocardial perfusion scan with 99mTc-Sestamibi
We present a female patient with atypical chest pain who was referred to our department for ischemia evaluation. 99mTc-MIBI myocardial perfusion scan with dipyridamole stress was performed. Sub-diaphragmatic activity in the hepatic tissue and then in the bowel loops caused severe overlap on the inferior wall even on consecutive delayed images. Dipyridamole stress was repeated for the...
[ 15 ] - Different aspects of transient ischemic dilation
Transient ischemic left ventricular dilation (TID) is a marker of severe and extensive coronary artery disease as well as an increased risk of adverse outcomes. The patients with more severe and extensive ischemia, multivessel-type of perfusion abnormality as well as patients with left anterior descending artery (LAD) territory perfusion abnormality have more probab...
[ 16 ] - Dipyridamole stress and rest gated 99mTc-sestamibi myocardial perfusion SPECT: left ventricular function indices and myocardial perfusion findings
Introduction: We investigated the difference in left ventricular ejection fraction (LVEF) and end-systolic volume(ESV) measured by gated myocardial perfusion SPECT (GSPECT) in the post-dipyridamole stress and rest periods, and compared the results with the perfusion patterns found in the conventional non-gated tomograms. Methods: 297 consecutive patients were studie...
[ 17 ] - Diuretic effect on the measurement of differential renal function using 99mTc-DMSA in patients with hydronephrosis [Persian]
Introduction: It has been suggested that calculation of differential renal function (DRF) using 99mTc-DMSA may lead to overestimation of the function of an obstructed kidney. The aim of this study was to evaluate the effect of diuretic administration on the determination of DRF using 99mTc-DMSA scintigraphy in patients with dilated pelvis. Methods: Thirty three patients, aged from 2 month...
[ 18 ] - Assessment of simulated patient motion and its effect on myocardial perfusion SPECT using two reconstruction methods (Filtered Backprojection;FBP and Iterative method) [Persian]
Introduction: Motion of the patient during myocardial perfusion SPECT could potentially results in false perfusion defects. The effect of different reconstruction methods on these artifacts is not studied. Clarification of the relation between the extent, severity and duration of motion with the resultant artifacts may be helpful in designing special soft wares for motion correction. This...
[ 19 ] - Diastolic left ventricular functional indices: Comparison between gated myocardial perfusion SPECT and echocardiography
Introduction: Many patients have only diastolic dysfunction without any abnormality in systolic function. We compared cardiac diastolic parameters obtained by gated myocardial perfusion SPECT (Gated SPECT) with those evaluated by echocardiography. Methods: Forty-nine patients (aged 37-85 years, 19 males and 30 women) underwent Gated SPECT and echocardiogr...
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