Somaye Ghahremani

nuclear medicine research center, ghaem hospital,mashhad,iran

[ 1 ] - Comparison of Treatment Response Achieved by Tablet Splitting Versus Whole Tablet Administration of Levothyroxine in Patients with Thyroid Cancer

Objective(s): TSH suppression by Levothyroxine consumption is a mainstay of thyroid cancer treatment. Tablet-splitting is a worldwide approach in dose adjustment in patients. However, it is highly recommended to evaluate the validity of tablet splitting for each distinctive drug by clinical trials before routinely using tablet halves in clinical practice. In this study we compared the effect of...

[ 3 ] - Use of Corticosteroid in Children with Unresponsiveness to Intravenous Immunoglobulin in Kawasaki Disease

Background Kawasaki Disease (KD) is a vasculitis with multi-organ involvementof unknown etiology; it is the most common cause of pediatric-heart diseases in developed countries. Treatment with Intravenous Immunoglobulin (IVIG) prevents coronary artery lesions; although there are some IVIG-resistant cases, combination therapy with corticosteroids and IVIG is one of the recommendations for treatm...

[ 4 ] - A wandering spleen detected by 99mTc-denatured RBC scan

A 23 day old infant patient underwent 99mTc-denatured RBC scanning for locating possible ectopic spleen in our department.  The scan showed no tracer activity in normal splenic bed in the left upper quadrant and an ectopic spleen was shown on the right side of abdomen inferior to the liver. 99mTc-denatured RBC scan is an easy and available method for splenic localization i...

[ 5 ] - Bone scintigraphy in diagnosing chronic recurrent multifocal osteomyelitis

A 10-year-old boy was referred to us for evaluation of FUO accompanied with bone pain in both calves. Three hours after intravenous injection of 13 mCi of 99mTc-MDP, whole body scan in multiple spot views was performed. The scan showed symmetrical areas of diffusely increased tracer uptake in multiple long bones. Histopathologic evaluation confirmed osteosclrosis and fibrotic changes...

[ 6 ] - Tc-99m Phytate lymphoscintigraphy: An excellent method for diagnosis of underlying cause of chylous ascites

We reported a 14 months old boy referred for evaluation of chylous ascites to our nuclear medicine department. Tc-99m Phytate was injected subcutaneously in his calves and whole body images as well as abdominal SPECT were performed. The SPECT images could localize an area of several intestinal lymphangiomata in the abdominal region. The abnormal region was surgically resected and the patient as...

[ 7 ] - Extra-striatal Uptake of 99mTc-TRODAT SPECT in a Cerebral Meningioma: A Case Report

We reported a 71 years old woman, with history of rest and postural tremor, bradykinesia and memory problems. In her dynamic MRI, a contrastenhanced tumor in the cerebellopontine (CP) angle was found which was compatible with a meningioma. 99mTc-TRODAT SPECT showed decreased activity in the left putamen, indicating idiopathic Parkinson disease. There was also a focus of increased activity on th...

[ 8 ] - Diastolic left ventricular functional indices: Comparison between gated myocardial perfusion SPECT and echocardiography

Introduction: Many patients have only diastolic dysfunction without any abnormality in systolic function. We compared cardiac diastolic parameters obtained by gated myocardial perfusion SPECT (Gated SPECT) with those evaluated by echocardiography. Methods: Forty-nine patients (aged 37-85 years, 19 males and 30 women) underwent Gated SPECT and echocardiogr...

[ 9 ] - Negative 99mTc-MIBI uptake in a parathyroid carcinoma: A case report

A 34 year old woman with malaise, polyuria and nocturia as well as nausea and vomiting referred to perform a thyroid scan due to right thyroid lobe mass. The scan showed a cold nodule in the right thyroid lobe. Serum calcium of 16.9, serum phosphorus of 1.8 and PTH of 1156 were noticed in laboratory tests. Parathyroid scan with 99mTc-MIBI showed no abnormal tracer activity in the nec...