Noushin Jalayer naderi

Dept. of Oral and Maxillofacial Pathology, Faculty of Dentistry, Shahed University, Tehran, Iran

[ 1 ] - Reporting an Experience: Improving the Feulgen Staining Technique for Better Visualizing of Nucleus

Among different staining methods used to demonstrate the nuclear abnormalities, Feulgen is one of the most reliable method. Feulgen staining is specific, sensitive method for evaluating the DNA damages.It has been shown that using non-DNA specific stains for monitoring the nuclear anomalies lead to false-positive or false-negative results. From self-experience, immersing the stained slides in h...

[ 2 ] - The Effect of Smoking on Mast Cells Density and Angiogenesis in Chronic Periodontitis

Background and objective:Gingival bleeding reduction in smokers has been associated with decreased blood vessel density. The mechanism of suppressive effect of cigarette smoking on blood vessel density is not precisely defined. The aim of this study was to evaluate the impact of smoking on angiogenesis by assessing mast cells density and VEGF expression in chronic peri...

[ 3 ] - The Relationship between Cytokeratins 7 and 20 Expression, and Prognostic Factors in Colon Adenocarcinoma: An Immunohistochemical Study

Background & Objective: The role of synchronized expression pattern of cytokeratin (CK) 7 and CK20 in the prognosis of colon adenocarcinoma is unclear. The current study aimed at determining the relationship between the expression of cytokeratins 7 and 20 and prognostic factors in colon adenocarcinoma. Methods: In the current cr...

[ 4 ] - بررسی ایمونوهیستوشیمیایی (C-kit) CD117 در تومورهای غدد بزاقی آدنویید سیستیک کارسینوما و پلی مورفوس آدنو کارسینومای درجه پایین

Background and Objective: Adenoid cystic carcinoma (ACC) and polymorphous low grade adenocarcinoma (PLGA) originate from ductal and myoepithelial salivary gland cells. They have a similar histologic appearance, but with different clinical behavior, treatment and prognosis. CD117 is a tyrosine kinase that is expressed by melanocytes, mastocytes and germinal cells. Our knowledge about its express...

[ 6 ] - آملوبلاستومای تک کیستی: بررسی کلینیکو پاتولوژیک 52 مورد

Introduction: Unicystic ameloblastoma is a subtype of ameloblastoma with some differences in clinical behavior such as lesser recurrence rate and aggressiveness. This lesion has 3 types: luminal, intraluminal and mural. The diagnosis of unicystic ameloblastoma is based on histopathology and radiological characteristics. Objective: This study attempts to determine the prevalence of unicystic a...

[ 7 ] - الگوی غشای پایه در سرطان‌های سلول سنگفرشی، سلول بازال و بازال سنگفرشی با استفاده از رنگ‌های پاس و رتیکولین

Background and Objective: Previous studies showed that basement membrane pattern is structuraly different in SCC and BCC tumors. BSCC is an epithelial malignant tumor with two histopathologic pattern similar to SCC and BCC. This study was aimed to compare the basement membrane pattern in SCC , BCC and BSCC tumors . Materials and Methods: In this laboratory study, the medical files of patients...

[ 8 ] - Mast cells density in fibrotic capsule of enchondroma and well-differentiated chondrosarcoma: a method for histopathologic differentiation

 Background: An enchondroma is a benign and a well-differentiated chondrosarcoma is an invasive chondroid tumor with high recurrence potential. In spite of biologic differences, these two tumors have very similar histopathologic appearance. It has been shown that the biologic nature of the connective tissue around benign and malignant tumors varies in the number of mast cells. The aim of this s...

[ 9 ] - A Concept Suggestion on the Effect of Cigarette Smoking in Inflammatory Destruction of Gingiva

Dear Editor, Cigarette smoking has destructive effect on periodontal tissue. The rates of loss of periodontal attachment and recession of gingival are higher in smokers than non-smokers (1-2). Previous studies on the inflammatory immune responses in smokers’ periodontitis have mainly focused on the role of neutrophils. Tumor necrosis factor–α, prostaglandin E2 and matrix metalloproteinase...

[ 10 ] - Micronucleus Assay of Buccal Mucosa Cells in Waterpipe (Hookah) Smokers: A Cytologic Study

Background & Objective: Micronucleus assay of buccal mucosa cells is a simple bio- monitoring method for diagnosing the genetic damages of toxic agents. The aim was to study the genotox...

[ 11 ] - Response to letter to the editor:” Is micronucleus assay suitable for cytogenetic biomonitoring the different ways to smoke? ”

Dear Editor, I was very pleased to find that the article” Micronucleus Assay of Buccal Mucosa Cells in Waterpipe (Hookah) Smokers: A Cytologic Study “(1) has attracted the attention of some readers and has created a few points for them. In my opinion, these points are good bases to overcome some concerns regarding micronucleus assay.