Hossein Keyvani
Dept of Virology, Iran University of Medical Sciences, Tehran, Iran.
[ 1 ] - Enzymatic Digestion Pattern of Varicella Zoster Virus ORF38 and ORF54 in Chickenpox Patients Using RFLP Technique
Background: Varicella zoster virus (VZV) causes chickenpox in children and zoster (zona) in the elderly. Using RFLP-PCR method for detection of VZV specific SNPs ORF38, 54 and 62 could distinguish the profile of VZV isolates. The aim of this study was to investigate enzymatic digestion pattern of VZV ORF38 and ORF54 in chickenpox patients using RFLP technique. <b...
[ 2 ] - نقش لنفوسیت‌هایT و سلول‌های کشنده طبیعی در پاتوژنز هپاتیت مزمن ویروسی
ویروس‌های هپاتیت B (HBV) و هپاتیتC (HCV) به علت توانایی بالای ایجاد عفونت پایدار، سیروز و سرطان کبد، منحصربه‌فرد هستند. اگرچه این دو ویروس در ساختمان ژنومی، سازوکار‌های تکثیر و چرخه زندگی خود، متفاوت هستند، اما دارای خصوصیات مشترکی ازجمله ماهیت غیر سایتوپاتیک و قابلیت القای بیماری کبدی مزمن هستند. تصور بر این است که وقایع ایمونولوژیکی، نقش مهمی را در پاتوژنز و پیامد این عفونت‌ها بازی می‌کند. ...
[ 3 ] - مروری بر انواع روش‌های Real-time PCR و بهینه‌سازی آن
روش Real-time PCR در سال‌های اخیر به عنوان روشی انتخابی جهت تشخیص بسیاری از بیماری‌های عفونی در آزمایشگاه ها مورد استفاده قرار گرفته است. با استفاده از این فن آوری، واکنش زنجیره پلیمراز توسط مولکول‌های گزارش گر فلورسنت انجام و از این طریق، تولید فرآورده‌های تکثیری طی هر چرخه واکنش PCR گزارش می‌شود. بدین ترتیب مجموعه‌ای از خصوصیات از جمله؛ حساسیت و اختصاصیت بالا، داده‌های قابل اعتماد و خ...
[ 4 ] - Trends in surveillance data of influenza virus in Tehran before decreasing dispatch of Iranian Hajj pilgrims to Mecca
Background: Respiratory infections, especially viral infections, are the most prevalent infection affecting Hajj pilgrims. Commonly 3 major human influenza viruses (A/H1N1, A/H3N2, and B) are responsible for these morbidities. The present study was conducted to develop a statistical report on human influenza in Hajj pilgrims. Methods: Nasal and throat samples were collected from 2...
[ 5 ] - Frequency of human Parvovirus B19 among patients with respiratory infection in Iran
Background: Human parvovirus B19 was known as one of the possible cause of mild respiratory tract diseases in previous studies. However, there are some reports of acute obstructive respiratory disease and severe pneumonia. The purpose of current study was to assess the prevalence and clinical features of parvovirus B19 in respiratory infection. Methods: This study was conducted on...
[ 6 ] - The prevalence of Human Papilloma Virus (HPV) infection in the oligospermic and azoospermic men
Background: Human papilloma virus (HPV) infection is one of the most common sexually transmitted diseases that affects men like women and infected cutaneous and mucosal squamous epithelium. The aim of the present study was to determine the prevalence of HPV in the semen of oligospermic, azoospermic and normal patients. Methods: From June 2012 to June 2013, a total of 90 individuals were enro...
[ 7 ] - Relation between parvovirus B19 infection and fetal mortality and spontaneous abortion
Background: Infection with parvovirus B19 may cause fetal losses including spontaneous abortion, intrauterine fetal death and non-immune hydropsfetalis. The aim of this study is to determine the frequency of parvovirus B19 in formalin fixed placental tissues in lost fetuses using real-time PCR method. Methods : In this cross-sectional study, 100 formalin fixed placental tissues with unknown...
[ 8 ] - Xenotropic Murine leukemia virus-related virus (XMRV) in Iranian HIV Patients
Background: Despite of isolation of Xenotropic murine leukaemia virus-related virus (XMRV) from the patients acquired prostate cancer in 2006 and patients with chronic fatigue syndrome in 2009, there have been controversial findings about its potential role in human diseases and frequencies in different population groups. In the present study, we aimed to determine the frequency of XMRV genome ...
[ 9 ] - Sero-prevalence of Herpes Simplex and Epstein Barr Viruses in HIV positive patients in Tehran
Abstract Background and Aims: The burden of HIV infection and disease continues to be a major global public health concern all over the world. This study was conducted to measure IgG antibody against EBV viral capsid antigen (EBV-VCA IgG), Herpes Simplex Type1, and 2 to determine the seroprevalence of this infection in HIV-positive population. Materials and Methods: A Cross-sectional st...
[ 10 ] - Incidence of Hepatitis B virus Surface Antigen (HBsAg) Mutations in Naïve Treated of Chronic Carriers from Tehran Metropolis, Iran
Abstract Background: Naturally occurred hepatitis B virus (HBV) with surface mutations in a variety of chronic hepatitis B (CHB) patients who have received no vaccine or HBIG bearing substitutions in surface protein, have been reported. Objectives: Current knowledge concerning the prevalence of these naturally occurring surface antigen mutations among Iranian carriers is limited. Patients and M...
[ 11 ] - الگوهای جدید درمانی برای عفونت ویروس هپاتیت C
Hepatitis C virus (HCV) infection has affected approximately 180 million people across the world. In most cases, HCV-infection remains chronic, which expose patients at high risk of cirrhosis and hepatocellular carcinoma. The rates of disease incidence and mortality diminish as a result of successful treatment of HCV infection. Until the recent years, despite the associated toxicities and l...
[ 12 ] - Clinical Presentations of Iranian Confirmed COVID-19 Patients at the Admission Time: A Preliminary Retrospective Study
Background and Aims: The current preliminary study aimed to assess the clinical symptoms of the 67 Iranian COVID-19 patients and investigate the possible beneficial effects of the naproxen compared to the standard therapeutic regimen. Materials and Methods: We assessed 67 COVID-19 patients. All COVID-19 cases were confirmed by computed tomography (CT) and real time-polymerase chain reaction te...