Marjan Heshmati
Dept. of Anatomy and Pathology, School of Medicine, Shahed University, Tehran, Iran
[ 1 ] - Temporal Correlation Of Bax Expression And Axotomy-Induced Motoneuronal Apoptosis In Adult Rats: A Morphometric, Ultrastructural And Immunohistochemical Study
Background and Objective: As apoptotic cell death is extremely involved in physiological development and many pathological situations such as cancer and neurodegenerative diseases, the understanding of its molecular machinery can be useful in designing new therapeutic strategies. The present study investigated the temporal expression of the proapoptotic protein Bax in adult spinal motoneuron...
[ 2 ] - Deprenyl Can Mediate Neuronal Protection Rather than Neuronal Rescue
Background and Objective: Deprenyl is a drug for the treatment of Parkinson’s disease, where the dopaminergic neurons are the target of this drug. Several reports also documented that deprenyl has an effect on the sensory and motor neurons. There are some reports about the mode of action of deprenyl on m...
[ 3 ] - Delayed Synaptic Changes in Axotomized Spinal Motoneurons of Newborn Rats Associated with Progressive Neuronal Loss: Immunohistochemical, Ultrastructural, and Quantitative Study
Background and Objective: Sciatic nerve transection is characterized by a rapid wave of motoneuron death associated with progressive synaptic lesions. The purpose of this study was to evaluate the long term synaptic changes. Materials and Methods: This basic study was carried out on paraffin- or resin-em...
[ 4 ] - اثر نوروپروتکتیوی استیل ال‌کارنیتین، پس از ضایعه فشار مکانیکی طناب نخاعی موش صحرایی بالغ
Background and Objective: Despite current efforts for treating the spinal cord injury (SCI), cell therapy and pharmacological methods have a great curing potential in this field. In this study, application of acetyl L carnitine as one of the possible pharmacologic approaches in SCI treatment was investigated. The effect of this material in adult rats suffering from spinal cord compression was e...
[ 5 ] - اثر عصاره آبی گیاه آلوئه‌ورا در بیان سیناپتوفیزین پس از ضایعه فشاری طناب نخاعی در موش صحرایی بالغ
مقدمه: صدمات طناب نخاعی یکی از عوامل ایجاد معلولیت است که امروزه یکی از آرزوهای جامعه پزشکی یافتن راهی برای به حداقل رساندن این عوارض می‌باشد. هدف: تأثیر عصاره آبی گیاه آلوئه‌ورا یا صبرزرد را در حفظ سلول‌های عصبی حرکتی و انتقال پیام عصبی در موش‌های صحرایی فلج شده. روش بررسی: 32 موش صحرایی ماده از انسیتو رازی استفاده شد. به طور تصادفی به 4 گروه تقسیم شدند: 1- گروه کنترل 2- گروه تحت تیمار با ...
[ 6 ] - دیدگاه دانشجویان پزشکی در مورد میزان یادگیری در روش نوین ادغام درس آناتومی اندام در سال تحصیلی 89-1388
Introduction: Following the "Integration Program" of general physician training curriculum recommended by the Department of Medical Education of Iranian Ministry of Health and Medical Education, several concerns raised towards the effect of this program. This study aimed to assess students' view towards integration of limb anatomy course to the pre-clerkship medical program in Iran. Method: The...
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