Parviz Owlia

Molecular Microbiology Research Center, Shahed University

[ 1 ] - Simultaneous Optimization of the Production of Organic Selenium and Cell Biomass in Saccharomyces Cerevisiae by Plackett-Burman and Box-Behnken Design

Selenium (Se) as a vital trace element has many biological activities such as anti-inflammation and anti-oxidation. Selenomethionine as an organic selenium plays a vital role in the response to oxidative stress. At present, Saccharomyces cerevisiae is one of the best microorganisms that has the ability to accumulate selenium. Production of Seleno-yeast was done by growing Saccharomyces cerevisi...

[ 2 ] - Simultaneous Optimization of the Production of Organic Selenium and Cell Biomass in Saccharomyces Cerevisiae by Plackett-Burman and Box-Behnken Design

Selenium (Se) as a vital trace element has many biological activities such as anti-inflammation and anti-oxidation. Selenomethionine as an organic selenium plays a vital role in the response to oxidative stress. At present, Saccharomyces cerevisiae is one of the best microorganisms that has the ability to accumulate selenium. Production of Seleno-yeast was done by growing Saccharomyces cerevisi...

[ 3 ] - ‌الگوی مقاومت به گروه‌های مختلف آنتی-بیوتیکی در جدایه‌های بالینی اسینتوباکتر بومانی در دو بیمارستان در تهران

Background and Objective: The global increase in resistance to antibiotics among clinical isolates of Acinetobacter baumannii is reported from several countries, but its true prevalence in Iran is less known. The objective of this study was determination of the frequency of resistance to different antibiotics among Acinetobacter baumannii isolated from patients in two hospitals in Tehran, Iran,...

[ 4 ] - Detection of Virulence Genes of Clostridium difficile in Children with Cancer by Multiplex PCR

Introduction: Toxigenic Clostridium difficile is the major cause of antibiotic-associated diarrhea, colitis, and pseudomembranous colitis. The pathogenicity of C. difficile is related to toxins A&B. Children with cancer are at risk of developing C. difficile infection (CDI) due to increased exposure to antibiotics, immunosuppression, and longer hospital stays. Recently, due to higher sensitivity...

[ 5 ] - Cloning and expression of hepatitis E virus ORF2 as a vaccine candidate

Introduction: Hepatitis E virus (HEV) is a fecal-oral transmitting virus which causes a chronic liver disease. ORF2 is an immunogen capsid protein of HEV that has been proposed to be used for Hepatitis E vaccine design. It is a 660-amino acid protein which includes an immunogenic region (residues 112-607). This protein has been expressed in complete and truncated forms, using different expressi...

[ 6 ] - Highlights of the final draft of the national policy document for science, technology and innovation in vaccine production in Iran

Introduction: Vaccination has been the most effective human intervention in alleviating human sufferings and death. Vaccine production in Iran has a long history however, in the face of a changing global landscape, it requires a new roadmap for research, development and production in the coming decades. Methods: This document was drafted based on Article A of the “Comprehensive National S...

[ 7 ] - اثر ضدمیکروبی اسانس مرزه (Satureja spp.) بر تولید همولیزین و بیوفیلم در استافیلوکوکوس اورئوس

درمان عفونت‌های ناشی از استافیلوکوکوس اورئوس به یک مشکل در جهان تبدیل شده است. این باکتری با داشتن عوامل بیماری‌زایی متعدد، یکی از پاتوژن‌های مهم به‌حساب می‌آید. هدف از این مطالعه ارزیابی اثر ضدمیکروبی 4 گونه از اسانس گیاه مرزه (Satureja khuzistanica Jamzad، Satureja bachtiarica Bunge، Satureja rechingeri Jamzad، Satureja mutica Fisch. & C. A. Mey.) بر تشکیل بیوفیلم و تولید همولیزین در باکتری ا...

[ 8 ] - اثر عصاره مایع رویی کشت و لیز سلولی مخمر پروبیوتیک ساکارومایسس سرویزیه بر تولید بیوفیلم و آلژینات در سودوموناس آئروژینوز

  زمینه و هدف : سودوموناس آئروژینوزا با استفاده از فاکتورهای بیماری زای متعدد یک پاتوژن فرصت طلب برای انسان می باشد . سودوموناس آئروژینوزا ظرفیت های قابل توجهی به مقاومت در برابر آنتی بیوتیک ها را نشان می دهد . در این مطالعه به بررسی اثر لیزات و مایع رویی کشت ساکارومایسس سرویزیه بر تولید بیوفیلم و آلژینات پرداخته شده است. مواد و روش‌کار: ابتدا عصاره مایع رویی کشت و نیز محلول لیز سلولی از سویه ب...