Ebrahim Salehifar

[ 1 ] - Cotreatment with Furosemide and Hypertonic Saline Decreases Serum Neutrophil Gelatinase-associated Lipocalin (NGAL) and Serum Creatinine Concentrations in Traumatic Brain Injury: A Randomized, Single-Blind Clinical Trial

Acute kidney injury (AKI) occurs both after traumatic brain injury (TBI) and after hypertonic saline administration; furosemide may be useful in preventing AKI indirectly. Serum neutrophil gelatinase-associated lipocalin (sNGAL) is superior to serum creatinine (sCr) in diagnosing early AKI. We compared the administration of hypertonic saline plus furosemide (HTS+F) versus hypertonic saline (HTS...

[ 2 ] - Sunitinib Induced Immune Thrombocytopenia

Sunitinib is an oral tyrosine kinase inhibitor which prevents tumor growth and metastatic progression. It was approved for treatment of advanced renal cell cancer, gastrointestinal stromal tumor and advanced pancreatic neuroendocrine tumors. It has several adverse reactions on multi organ systems including hematologic system. Although the neutropenia and thrombocytopenia commonly happens as Gra...

[ 3 ] - Determination of antibiotics consumption in Buali_Sina Pediatric Hospital, Sari 2010-2011

Aim: The increasing prevalence of antibiotic-resistant bacteria is a major health-care problem worldwide. WHO recommends DID (daily defined dose/ 100 Inhabitant /day) as a standard tool for measurement of antibiotic consumption. Since there was not any information regarding the antibiotics usage pattern in the north of Iran, the aim of this study was determine this in our centre.Method: This cr...

[ 4 ] - An Unreported Clindamycin Adverse Reaction: Wrist Monoarthritis

Clindamycin is a lincosamide antibiotic which is approved for the treatment of anaerobic, streptococcal and staphylococcal infections. There has been an increased interest in the use of clindamycin since it achieves high intracellular levels in phagocytic cells, high levels in bone and appears to have an antitoxin effect against the toxin elaborating strains of streptococci and staphylococci. C...

[ 5 ] - Cotreatment with Furosemide and Hypertonic Saline Decreases Serum Neutrophil Gelatinase-associated Lipocalin (NGAL) and Serum Creatinine Concentrations in Traumatic Brain Injury: A Randomized, Single-Blind Clinical Trial

Acute kidney injury (AKI) occurs both after traumatic brain injury (TBI) and after hypertonic saline administration; furosemide may be useful in preventing AKI indirectly. Serum neutrophil gelatinase-associated lipocalin (sNGAL) is superior to serum creatinine (sCr) in diagnosing early AKI. We compared the administration of hypertonic saline plus furosemide (HTS+F) versus hypertonic saline (HTS...

[ 6 ] - Sunitinib Induced Immune Thrombocytopenia

Sunitinib is an oral tyrosine kinase inhibitor which prevents tumor growth and metastatic progression. It was approved for treatment of advanced renal cell cancer, gastrointestinal stromal tumor and advanced pancreatic neuroendocrine tumors. It has several adverse reactions on multi organ systems including hematologic system. Although the neutropenia and thrombocytopenia commonly happens as Gra...

[ 7 ] - Determination of antibiotics consumption in Buali_Sina Pediatric Hospital, Sari 2010-2011

Aim: The increasing prevalence of antibiotic-resistant bacteria is a major health-care problem worldwide. WHO recommends DID (daily defined dose/ 100 Inhabitant /day) as a standard tool for measurement of antibiotic consumption. Since there was not any information regarding the antibiotics usage pattern in the north of Iran, the aim of this study was determine this in our centre.Method: This cr...

[ 8 ] - An Unreported Clindamycin Adverse Reaction: Wrist Monoarthritis

Clindamycin is a lincosamide antibiotic which is approved for the treatment of anaerobic, streptococcal and staphylococcal infections. There has been an increased interest in the use of clindamycin since it achieves high intracellular levels in phagocytic cells, high levels in bone and appears to have an antitoxin effect against the toxin elaborating strains of streptococci and staphylococci. C...

[ 9 ] - ارزیابی مصرف پنتوپرازول تزریقی در یک بیمارستان آموزشی در شمال ایران، 1395

Background and purpose: Proton pump inhibitors (PPIs) are one of the main therapeutic agents for acid-dependent diseases. Inappropriate use of this group of drugs especially Intravenous form of pantoprazole can lead to unnecessary cost. The aim of this study was to assess the IV Pantoprazole utilization in a teaching hospital in North of Iran. Materials and methods: This cross sectional study ...

[ 10 ] - اپیدمیولوژی ژن های اشریشیاکلی مولد بتالاکتاماز وسیع الطیف در عفونت های ادراری کودکان در شمال ایران

Background and purpose: Extended Spectrum Beta Lactamases (ESBLs) are one of the most important health care issues all over the world. Uropathogenesis are responsible for life threatening infections in children. In this study we aimed at investigating the epidemiology of CTX, TEM and VEB genes in pediatric UTI. Materials and methods: Urine samples were collected during six months in Sari Bou...

[ 11 ] - بررسی عوامل ایجاد کننده سوختگی و چگونگی پیامد آنها در بیماران بستری در بخش سوختگی بیمارستان زارع ساری، سال 86-85

Background and Purpose: It has been reported that the cause of burn is an important factor in the determination of prognosis and outcome. Due to different results of various centers, we conducted this study to determine the relationship between cause of burn and outcomes including rate of infection, costs and mortality in Zare Hospital. Materials and Methods: This prospective study, has be...

[ 12 ] - How rational Aminoglycosides are being used in critically ill patients? Results from a teaching hospital in north of Iran

Background: Resistance to antimicrobial agents including aminoglycosides (AGs) is a great concern that is mainly related to inappropriate use. Since there were not adequate data regarding how rationally AGs are being prescribed in our critically ill patients, this study was conducted to determine the main issues in the area of appropriate use of this antibiotic class. Methods: One hundred...

[ 13 ] - Comparison of the incidence and severity of side effects profile of FOLFOX and DCF regimens in gastric cancer patients

Abstract Introduction: Gastric cancer is the fourth common cancer and the second leading cause of cancer death worldwide. Due to lack of adequate information on the side effects of chemotherapy regimens in treatment of gastric cancer, this study was aimed to determine the side effects of two common chemotherapy regimens of gastric cancer. Methods: This prospective study was conducte...

[ 14 ] - Effects of minocycline on neurological outcomes in patients with acute traumatic brain injury: a pilot study

Traumatic brain injury (TBI) is a public health problem worldwide. Secondary damage of brain injury begins within a few minutes after the trauma and can last a long time. It can be reversible, unlike primary injury. Therefore, therapeutic intervention can be used. The aims of this study were to assess the effects of minocycline on neurological function and serum S100B protein and neuron-specifi...

[ 15 ] - Comparison of the incidence and severity of side effects profile of FOLFOX and DCF regimens in gastric cancer patients

Abstract Introduction: Gastric cancer is the fourth common cancer and the second leading cause of cancer death worldwide. Due to lack of adequate information on the side effects of chemotherapy regimens in treatment of gastric cancer, this study was aimed to determine the side effects of two common chemotherapy regimens of gastric cancer. Methods: This prospective study was conducte...

[ 16 ] - Effects of minocycline on neurological outcomes in patients with acute traumatic brain injury: a pilot study

Traumatic brain injury (TBI) is a public health problem worldwide. Secondary damage of brain injury begins within a few minutes after the trauma and can last a long time. It can be reversible, unlike primary injury. Therefore, therapeutic intervention can be used. The aims of this study were to assess the effects of minocycline on neurological function and serum S100B protein and neuron-specifi...

[ 17 ] - Role of Pharmacist in Reducing the Rate of Drug Interactions; An Experience from North of Iran

Background and purpose: Drug interactions are one of the serious subsets of medication errors and occur when the effects or toxicity of one drug are affected by another. This study aimed to investigate drug interactions and the role of pharmacist in reducing drug interactions in Ramsar Imam Sajjad Hospital, Iran. Materials and methods: This cross-sectional study was performed in all prescripti...

[ 18 ] - Efficacy of Sucralfate Ointment in Prevention of Acute Proctitis in Cancer Patients: a Randomized Controlled Clinical Trial

Background: Acute radiation proctitis (ARP) is a usual adverse effect in patients undergoing pelvic radiotherapy. The symptoms include diarrhea, rectal blood or mucus discharge, fecal urgency and tenesmus with pain. Sucralfate, an aluminum-based salt of sucrose octasulfate, is a cytoprotective agent that forms a coating barrier at injured sites by adhering to mucoproteins. It has been used in t...