Sepideh Arbabi Bidgoli

Pharmaceutical Sciences Research Center, Islamic Azad University (IAUPS), Pharmaceutical Sciences Branch, Tehran, Iran.|Department of Toxicology & Pharmacology, Islamic Azad University, Pharmaceutical Sciences Branch (IAUPS), Tehran, Iran.

[ 1 ] - Toxicity Assessment of Asteraceae Centaurea Repens L Extract in Mice

The species Asteraceae Centaurea repens (Asteraceae), known as Acroptilon repens, andTalkhe in persian is used in folk medicine as an emetic, anti-epileptic, and anti-malaria herbin many parts of the world but its toxic effects have not determined yet. This study aimed toevaluate the acute and subchronic toxicity of this extract to find its possible adverse healtheffects through clinical, hemat...

[ 2 ] - Mutagenic Effects of NanosilverConsumer Products: a new Approach to Physicochemical Properties

Serious concerns have been expressed about potential health risks of Nano silver containing consumer products (AgNPs) therefore regulatory health risk assessment on such nanoparticles has become mandatory for the safe use of AgNPsinbiomedicalproducts with special concerns to the mutagenic potentials. In this study, we examined the inhibitory and mutagenicity effects of AgNPs in three different ...

[ 3 ] - Micronucleus Investigation in Buccal Mucosal Cells of Young Waterpipe Tobacco Smokers in Tehran

Waterpipe Tobacco Smoke(WTS) is an unhealthy life style that may increase the risk of genotoxic responses and chronic diseases such as cancer. Micronucleus test is a successful and reliable method which is used for screening of genetotoxic responses of whole body and also for screening those people who had already exposed to genotoxic compounds. In this study, specific questionnaires were desig...

[ 4 ] - Ames Mutagenicity Assessment of Flavored Water Pipe Tobacco Products :A Cross Sectional Study in Tehran

Waterpipe smoking has become a global youth trend especially in the Middle East countries and Iran . The aim of this study was to determine the mutagenic effects of three most popular flavored tobaccos by four different salmonella typhimurium strains and compare the possible mutagenic effects of the test samples. Ames mutagenicity assessment was conducted according to the OECD guideline using T...

[ 5 ] - Role of endocrine disrupting chemicals on the tissue levels of AhR and sex steroid receptors in breast tumours

Breast cancer affects Iranian women at least one decade younger than their counterparts in othercountries and the incidence of breast fibroadenoma is growing in the last two decades in Tehran. Thisstudy aimed to compare the AhR levels in premenopausal breast cancer and breast fibroadnemo withappropriate normal groups. Possible associations of AhR with lifestyle and reproductive risk factorsand ...

[ 6 ] - Increased risk of endometriosis by long term exposure to xenoestrogens: A case control study in Iranian women

Aims of the study: Endometriosis is a prevalent gynecologic disorder in young women at reproductiveage but the underlying risk factors have not identified yet in Iran and other neighboringcountries. Persistent exposure to environmental endocrine disrupting chemicals (EDCs) in particulardioxins, PAHs and polychlorinated biphenyls (PCBs) with xenoestrogenic potentials have beenhypothesized in the...

[ 7 ] - Dermal toxicity of Colloidal Nanosilver in Albino Rabbit: A New Approach to Physicochemical Properties

Objective(s): Silver nanoparticles have been widely used as new potent antimicrobial agents in cosmetic and hygienic products, as well as in new medical devices. Serious concerns have been expressed on the potential health risks of dermal applications of nanosilver containing consumer products (AgNPs), therefore regulatory health risk assessment has become necessary for the saf...

[ 8 ] - Toxicity Assessment of Asteraceae Centaurea Repens L Extract in Mice

The species Asteraceae Centaurea repens (Asteraceae), known as Acroptilon repens, andTalkhe in persian is used in folk medicine as an emetic, anti-epileptic, and anti-malaria herbin many parts of the world but its toxic effects have not determined yet. This study aimed toevaluate the acute and subchronic toxicity of this extract to find its possible adverse healtheffects through clinical, hemat...

[ 9 ] - Mutagenic Effects of NanosilverConsumer Products: a new Approach to Physicochemical Properties

Serious concerns have been expressed about potential health risks of Nano silver containing consumer products (AgNPs) therefore regulatory health risk assessment on such nanoparticles has become mandatory for the safe use of AgNPsinbiomedicalproducts with special concerns to the mutagenic potentials. In this study, we examined the inhibitory and mutagenicity effects of AgNPs in three different ...