Mehran Zarghami

Psychiatry and Behavioral Sciences Research Center, Addiction Institute and Department of Psychiatry, Mazandaran University of Medical Sciences

[ 1 ] - Effectiveness of Vitamin D Supplement Therapy in Chronic Stable Schizophrenic Male Patients: A Randomized Controlled Trial

In this study, the aim was to determine whether adding vitamin D to the standard therapeutic regimen of schizophrenic male patients with inadequate vitamin D status could improve some aspects of the symptom burden or not. This study was an open parallel label randomized clinical trial. Eighty patients with chronic stable schizophrenia with residual symptoms and Vitamin D deficiency were recruit...

[ 2 ] - Effectiveness of Vitamin D Supplement Therapy in Chronic Stable Schizophrenic Male Patients: A Randomized Controlled Trial

In this study, the aim was to determine whether adding vitamin D to the standard therapeutic regimen of schizophrenic male patients with inadequate vitamin D status could improve some aspects of the symptom burden or not. This study was an open parallel label randomized clinical trial. Eighty patients with chronic stable schizophrenia with residual symptoms and Vitamin D deficiency were recruit...

[ 3 ] - تعیین بررسی وضعیت روانشناختی و رفتاری شایع و غیر شایع در معاف شدگان خدمت سربازی متقاضی دریافت گواهینامه رانندگی

Background and purpose: Some people are eligible for psychiatric exemptions before or during military service. This study aimed to investigate the common and uncommon psychological and behavioral situation in applicants for driving license exempt from military service. Materials and methods: In this cross-sectional study, the population included applicants for driving license with psychiatric ...

[ 4 ] - راهنمای بالینی پنهان‌کردن داروهای خوراکی روان‌پزشکی در بیماران روان‌پزشکی: چالش‌ها و راهکارها

Drug therapy is the core of the treatment of psychiatric disorders. Psychotropic drugs can reduce the severity of mental illness and improve the outcomes of these disorders if they are used properly. One of the main challenges in psychiatric patients, especially patients who did not have enough insight into their illness, is lack of adherence to treatment. In the present study, we have tried to...

[ 5 ] - Study of Methamphetamine Use in Patients Referred to Emergency Ward of a General Hospital at North of Iran in 2017

Background: Acute use of methamphetamine affects the sympathetic system and causes symptoms like tachycardia, hypertension (HTN), tachypnea, peripheral blood vessels constriction, hyperthermia, and mydriasis that can lead to many medical complications. Thus, this study aimed to evaluate the use of methamphetamine, clinical symptoms, and admission causes in pati...

[ 6 ] - Iranian Female Methadone Patients and the Perceived Educational Needs Related to Human Immunodeficiency Virus

Background: Iranian female methadone patients are at risk of human immunodeficiency virus (HIV) due to involvement in high-risk sexual behaviours and/or needle sharing. The present study aimed to explore the perceived educational needs related to HIV among a group of Iranian female methadone patients. Methods:The research design was qualitativ...

[ 7 ] - Efficacy of Smoking Cessation on Stress, Anxiety, and Depression in Smokers with Chronic Obstructive Pulmonary Disease: A Randomized Controlled Clinical Trial

Background: Stress, anxiety, and depression have been reported as very common comorbidities in smokers with chronic obstructive pulmonary disease (COPD). This study was aimed to investigate the effectiveness of smoking cessation on stress, anxiety, and depression in smokers with COPD. Methods: Three block-randomized controlled trial groups with a block size of 6 and 9 including guided self-chan...

[ 8 ] - An Overview of the Research Reports on Addiction in Iranian Journals from 2010 to 2015

Background: The articles and research reports presented in the scientific journals are selected without a proper critical appraisal in many cases. This is a major problem, as it leads to the opinions of the experts being neglected in many of these scientific journals. A descriptive study was done in fall and winter of 2016.Methods: Journals were identified searching the electronic databases, in...

[ 9 ] - Loperamide Dependence: A Case Report

Background: Loperamide is used as an antidiarrheal drug and is available over-the-counter. It cannot pass the blood-brain barrier and it does not have a considerable abuse potential. It can lead to dangerous cardiac arrhythmia.Case Report: Herein, we report a 35-year-old man with a 13-year history of abusing opioids who had undergone detoxification for four times during this period. He underwen...

[ 10 ] - Willingness to Receive Treatment for Hepatitis C among Injecting Drug ‎Users on Methadone Program: Implications for Education and Treatment

Background: Hepatitis C virus (HCV) is common among people who inject drugs (PWID) on methadone program in Iran (Persia). However, a few PWID on methadone program report willingness to receive HCV treatment. This study aimed to assess the factors which were associated with willingness to receive HCV treatment in a group of PWID on methadone program in Iran.Methods: We surveyed 187 PWID at seven...

[ 11 ] - Characteristics of an Online HIV Education Program for Iranian Female Methadone Patients: The First Study

Objectives:  Female methadone patients need specific education on HIV. However, few studies have been conducted on the essential characteristics of designing an online HIV education program for this population. Therefore, the current qualitative study aimed at addressing this research gap. Methods: Semi-structured interviews were conducted with 34 female patients and 19 methadone treatment pro...

[ 13 ] - Evaluation of the efficacy and safety of pregabalin as an adjuvant to antipsychotics in patients with chronic schizophrenia: a six-week pilot double-blind placebo-controlled trial

Introduction and objectives: Antipsychotics or dopamine receptor antagonists are the major components of treatment but about 10-20% of patients with schizophrenia do not benefit from treatment with antidopaminergic agents, indicating other neuronal systems may be involved in this disorder (2). Dysregulation of both excitatory and inhibitory mechanisms N-Methyl-D-aspartic acid (NMDA) and γ-Amino...

[ 14 ] - Substance-Related Mortality in Iran: A Retrospective Study of National Registered Data (2014-2018) Using Joinpoint Regression Analysis

Background and purpose: This study was carried out to analyze the trend of death due to substance abuse and related factors in Iran in order to design and implement preventive and therapeutic interventions for substance related deaths. Materials and methods: In this cross-sectional study, we investigated the data of 6810 deaths caused by drug abuse, registered in the "System of Registration an...