Maryam Karkhane

aGastroenterology and Liver Diseases Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. b Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Shahid Beheshti University of Medical Sciences, Tehran

[ 1 ] - Annual Antibiotic Related Economic Burden of Healthcare Associated Infections; a Cross-Sectional Population Based Study

Abstract: So far, too little attention has been paid to total burden of healthcare associated infections (HAIs) in Iran. In present study, we aimed to assess the rate of HAIs, as well as economic burden of hospitalization and antibiotic related cost associated with HAIs at training Taleghani hospital in Iran and to compare our results with NNIS system. This research to date for the first time h...

[ 2 ] - Annual Antibiotic Related Economic Burden of Healthcare Associated Infections; a Cross-Sectional Population Based Study

Abstract: So far, too little attention has been paid to total burden of healthcare associated infections (HAIs) in Iran. In present study, we aimed to assess the rate of HAIs, as well as economic burden of hospitalization and antibiotic related cost associated with HAIs at training Taleghani hospital in Iran and to compare our results with NNIS system. This research to date for the first time h...

[ 3 ] - Genetic Variations in Host Factors and their Critical Role on HCV Medication

Although standard treatments are nearly life-saving in hepatitis C patients, all patients equalldon’t respond to such medications. To achieve an efficient therapeutic response in all patients, medications should individually alter based on genetic factor variations. Hence, having more detailed knowledge of the affective factors on the disease promotion could help us to organize an appropr...

[ 4 ] - L-Asparaginase-producing Rouxiella Species Isolation, Antileukemia Activity Evaluation, and Enzyme Production Optimization

Background: L-Asparaginase (L-Asp) is used as an efficient anti-cancer drug, especially for acute lymphoblastic leukemia (ALL). Currently, two bacterial asparaginase isoenzymes are used for cancer treatment. Therefore, this research focused on isolating native bacteria with the ability to produce L-Asp.  Materials and methods: L-Asp producing bacteria were isolated from soil samples on 9K medi...