Saman Ahmad Nasrollahi
Center for Research and Training in Skin Diseases and Leprosy (CRTSDL), Tehran University of Medical Sciences, Tehran, Iran
[ 1 ] - Amitriptyline 2% cream vs. capsaicin 0.75% cream in the treatment of painful diabetic neuropathy (Double blind, randomized clinical trial of efficacy and safety)
Because of less systemic side effects of topical medications in pain relief of the painful form of diabetic peripheral neuropathy, this study aimed to compare the effect of amitriptyline and capsaicin cream in relieving pain in this condition. In this randomized, double-blind and non -inferiority trial, 102 patients received amitriptyline 2% and capsaicin 0.75% creams 3 times a day for 12 week...
[ 2 ] - Amitriptyline 2% cream vs. capsaicin 0.75% cream in the treatment of painful diabetic neuropathy (Double blind, randomized clinical trial of efficacy and safety)
Because of less systemic side effects of topical medications in pain relief of the painful form of diabetic peripheral neuropathy, this study aimed to compare the effect of amitriptyline and capsaicin cream in relieving pain in this condition. In this randomized, double-blind and non -inferiority trial, 102 patients received amitriptyline 2% and capsaicin 0.75% creams 3 times a day for 12 week...
[ 3 ] - مروری بر درمان‌های رایج شپش سر
Pediculosis infection is seen in all age group and different societies and several treatment have been suggested and marketed. In this study, we try to explain the difference of anti-lice products in Iran. Also it is necessary to mention that Anti-lice products are not effective alone, therefore to eliminate head lice infection the use of appropriate anti-lice combs is recommended.
[ 4 ] - تعیین مقدار فاکتور حفاظتی اشعه‌ی فرابنفش A در کرم‌های ضدآفتاب
Sunscreen products are among the most important ways for skin protection against sunburn, early skin aging and skin cancer. Due to existing wide variation of sunscreens, it is necessary to assure their protection ability against the sun damage. Performance assessment of sunscreen products against UVA is expressed by sun UVA protection factor (UVA-PF). Because currently these factors are determi...
[ 5 ] - تعیین مقدار Sun Protection Factor (SPF) در کرم‌های ضدآفتاب به روش درون‌تن
Application of sunscreens is one of the most important ways for skin protection against sunburn, early skin aging and skin cancer. Due to variety of sunscreen products, it is necessary to assure their protection ability against the sun’s damages. Performance assessment of sunscreens against UVB expressed by sun protection factor. Due to great cost of determination methods of this factor in for...
[ 6 ] - ارزیابی بیخطری کرم‌های ضددرماتیت ازطریق اندازه‌گیری شاخص‌های بیوفیزیکی پوست: کارآزمایی بالینی دارای گروه شاهد فاز I
Background and Aim: Dermatitis or eczema is an itchy skin disorder which is usually caused by the skin inflammatory reaction in response to combination of genetic and environmental factors. This study was aimed to assess the safety of anti-dermatitis creams and possible side effects on human volunteers through measuring the skin biophysical parameters with non-invasive methods. Methods: Two ...
[ 7 ] - ارزیابی بیخطری محلول موضعی مینوکسیدیل 5% + بابونه‌ی 7%
Background and Aim: Androgenetic alopecia (AGA) is the most common form of alopecia in men, worldwide and topical minoxidil appears to be the most effective and safe treatment for AGA beside oral finasteride. Safety assessment of topical minoxidil formulation could be conducted using in vivo studies on human volunteers. Using skin biophysical parameters is a fast and noninvasive method for safe...
[ 8 ] - فراورده‌های مرطوب‌کننده‌ی پوست
The function of the horny layer of the skin as a barrier is to protect the underlying tissues from infection, dryness, and mechanical stress. Disruption of this function results in increased transepidermal water loss (TEWL) and is associated with conditions like atopic dermatitis and other chronic skin diseases. Moisturizers have been shown to improve these conditions through restoration of the...
[ 9 ] - بیخطری دو فرآوردهی مرطوب‌کننده: کارآزمایی بالینی دارای گروه شاهد فاز I
Background and Aim: Moisturizers have important roles in the treatment of dry skin. Their safety has to be evaluated on human volunteers in order to assess their potential skin irritation. Measurements of skin biophysical parameters can be used as fast and noninvasive methods to assess any harmful effect of cosmetic formulations on the skin sites where those products are applied. Methods: Tw...
[ 10 ] - بیخطری 5 فرآوردهی ضدآفتاب: کارآزمایی بالینی دارای گروه شاهد فاز I
Background and Aim: Sunscreens are an important part of photoprotection strategy. They are exposed to strict safety evaluation using human subjects such as in vivo studies of skin irritation. Biophysical parameters measurements could be used as fast and noninvasive methods to measure any destructive effect of cosmetic formulations on skin application sites. Methods: Five sunscreens were sel...
[ 11 ] - ترکیبات موجود در فرآورده‌های ضدآفتاب: اکسید روی
Although ultraviolet rays constitute a small portion of the sunlight, they are destructive on skin. Ultraviolet rays cause sunburn, skin damage and skin cancers. Sunscreens are one of the most widely used cosmetic products which protect skin from cancer or other damages. There are two categories of sunscreen agents: chemical and physical. Physical sunscreens containing zinc oxide work through t...
[ 12 ] - تعیین غلظت سورفکتانت‌های آنیونی و آمفوتری موجود در شامپوها به کمک روش تیتراسیون پتانسیومتری
Background and Aim: Shampoos are surfactant systems to clean hair and body. Two kinds of surfactants are generally used in shampoo formulations: anionic and amphoteric. These agents, especially anionic ones may cause skin irritation and dryness after bathing. So, using a simple and fast method to determine the types and concentrations of surfactants can help to choose a product with high effica...
[ 13 ] - ترکیبات موجود در فرآورده‌های ضدآفتاب: دی‌اکسیدتیتانیوم (TiO2)
The use of sunscreens should also be recommended in order to work against all kind of ultarviolet (UV)-induced skin damage such as photoallergies, skin wrinkles, sunburn or even skin cancer. Sunscreens contain chemical filters (organic absorb regularly UVB radiation) and physical filters (e.g., TiO2 and ZnO). The second group has been said to reflect and scatter UVB and UVA radiation. TiO2 is ...
[ 14 ] - درمان‌های دارویی بیماری رُزاسه
Rosacea is a chronic inflammatory disease which presents with condition with a prevalence erythema and inflammatory lesions on central face. Rosacea has significant impact on quality of life of patients hence lowering confidence and harmful for social positions Study of effective medications improves quality of life of patients. In this study we tried to review effective medical treatments for...
[ 15 ] - Comparative clinical assessment of two nasolabial hyaluronic acid fillers: A double-blind, randomized controlled trial
Background: Various fillers have been used for the correction of nasolabial folds. This study investigated the efficacy and safety assessment of two hyaluronic acid (HA) fillers on moderate nasolabial folds. Methods: This study randomized 10 volunteers, aged 35 to 49 years, with moderate nasolabial folds. Volunteers received injections of HA A and HA B gels into the right or left skin folds. Th...
[ 16 ] - Potential of Trachyspermum ammi (ajwain) Gel for Treatment of Facial Acne vulgaris: a Pilot Study with Skin Biophysical Profile Assessment and Red Fluorescence Photography
Background and objectives: Acne vulgaris is one of the most common dermatologic conditions. The available anti-acne treatments are not satisfactory and safe. In...
[ 17 ] - A review of the microneedles for transdermal drug delivery
Microneedles consist of micron-sized projections similar to needles. They are capable of piercing through the stratum corneum and increase the permeation of active ingredients. Besides active pharmaceutical ingredients, microneedles can also deliver cosmetic agents, biotherapeutics like insulin and vaccines and also are used in diagnostic purposes. This article examines the types of microneedle...
[ 18 ] - Anatomy and physiology of newborns and introduction of various and specific skin care products
Full term newborns have a skin that rapidly develops towards adult skin. From the anatomical point of view, the differences are limited, but some changes at birth are responsible for the physiological differences between the skin of infants and adults. Newborns skin exhibits the same barrier function and absorption properties as adults, but external conditions for newborns may be different from...
[ 19 ] - Reviewing the physiology of human perspiration and introducing different types of antiperspirant and deodorant products
Habits since the introduction of the first commercial antiperspirant and deodorant, the use of these products have played an increasing role in a person's personal care. This article studies the physiology of human perspiration and responsible compounds for body odor. It also describes the function, classification, and differences between antiperspirants and deodorants.
[ 20 ] - Effects of infrared, blue light and UVA-II on human skin
Knowledge about environmental factors that are aggressive to skin has increased in recent years. Although concern previously focused primarily on UVA and UVB, this has broadened to contain damage from pollution, tobacco smoke, other ambient toxins, infrared light, blue light and UVA-II. This article reviews the negative effects of infrared, blue light and UVA-II on skin. Potential protective a...
[ 21 ] - Reviewing the nanotechnology in cosmeceuticals
Cosmeceuticals are the fastest growing segment of the personal care industry, and a number of topical cosmeceutical treatments for conditions such as photoaging, hyperpigmentation, wrinkles, and hair damage have come into widespread use. In the cosmeceutical arena nanotechnology has played an important role. Using new techniques to manipulate matter at an atomic or molecular level, opening up n...
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