Azam Sadeghian

Department of Physiology and Neurophysiology Research Center, School of Medicine, Shahed University, Tehran, Iran.

[ 1 ] - Antiepileptic and Antioxidant Effect of Brassica nigra on Pentylenetetrazol-Induced Kindling in Mice

Considering the high rate of epilepsy today, with respect to the insufficiency of the available therapies, new strategies and methods are recommended for medical treatment of epileptic patients. Therefore, the present study experimentally investigated the anticonvulsant effect of a herbal medicine candidate brassica nigra, by using kindling method. Sixty male mice were randomly selected and div...

[ 2 ] - Methadone and valproate combination effect on acquisition and expression of morphine dependence and tolerance in male mice

Abstract Background and Objective: According to the issue of dependence and tolerance in addicted patients, the inefficiency of existing treatments and the new recommendation for drug combination therapy for diseases in modern pharmacology, the present study examined the effect of methadone and valproate combination on morphine dependence and tolerance. Materials and Methods: Ninety-eight male ...

[ 3 ] - Anti-inflammatory effect of alcoholic Urtica dioica extract in male NMRI rats

Background and Objective: Regarding side effects of acute and especially chronic inflammation and incomplete treatment of patients suffering from these side effects, the new and effective strategies are needed. For this purpose, in the present study, we scientifically evaluate an introduced folk herb Urtica dioica, for treatment of inflammation. Materials and Methods: The Sham, control and trea...

[ 4 ] - Antiepileptic and Antioxidant Effect of Brassica nigra on Pentylenetetrazol-Induced Kindling in Mice

Considering the high rate of epilepsy today, with respect to the insufficiency of the available therapies, new strategies and methods are recommended for medical treatment of epileptic patients. Therefore, the present study experimentally investigated the anticonvulsant effect of a herbal medicine candidate brassica nigra, by using kindling method. Sixty male mice were randomly selected and div...

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