Farnaz Nikbakht
Department of Physiology Iran University of Medical Sciences
[ 1 ] - The Effect of Acute Corticosterone Administration on Retrieval of Remote and Recent Memory in the Rat
Background and Objective: It is well known that stress and glucocorticoid, modulate memory processing, though the result is completely dependent on the time of stress induction. This study investigated the effect of acute corticosterone administration on memory retrieval of recent and remote memory in a 4 trials/day (low- intensity learning) or 8 trials/ day (high- intensity learning) Morris wa...
[ 2 ] - The effect of rosemary extract on spatial memory, learning and antioxidant enzymes activities in the hippocampus of middle-aged rats
Background: The Rosemary extract (RE) possesses various antioxidant, cytoprotective and cognition-improving bioactivities. In this study, we postulated which doses of RE have a more effect on the hippocampus of middle-aged rats. Methods : In this experimental study, thirty-two middle-aged male Wistar rats were fed by different doses (50,100 and 200 mg/kg/day) of RE (containing 40% carnosic ...
[ 3 ] - Evaluation of the neuroprotective, anticonvulsant, and cognition-improvement effects of apigenin in temporal lobe epilepsy: Involvement of the mitochondrial apoptotic pathway
Objective(s): Cognitive deficit is a common problem in epilepsy. A major concern emergent from the use of antiepileptic drugs includes their side effects on learning and memory. Herbal medicine is considered a complementary and alternative therapy in epilepsy. Apigenin is a safe flavone with antioxidant properties. However, there is little information about the benefic...
[ 4 ] - Protective Role of Apigenin Against Aβ 25-35 Toxicity Via Inhibition of Mitochondrial Cytochrome c Release
Introduction: Cognitive dysfunction is the most common problem of patients with Alzheimer disease (AD). The pathological mechanism of cognitive impairment in AD may contribute to neuronal loss, synaptic dysfunction, and alteration in neurotransmitters receptors. Mitochondrial synapses dysfunction due to the accumulation of amyloid beta (Aβ) is one of the earliest pathological features of AD. Th...
نویسندگان همکار