Leila Rouhi
Department of Animal Physiology, Faculty of Basic Sciences, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
[ 1 ] - The Beneficial Effect of Hydro-alcoholic Extract of Punica Granatum L. Leaves & Flower on Ethylene Glycol-Induced Kidney Calculi in Rats
Background & Aim: Punica granatum L. (pomegranate) is a widely used plant that has high nutritional value .This study evaluated prevention effect of hydro alcoholic extract of Punica granatum flower and leaves ethylene glycol-induced Nephrolithiasis in Wistar rats. Experimental: 20 male Wistar rats were randomly divided into 4 equal groups. G...
[ 2 ] - Effect of the extract from Gundelia tournefortii on immature mouse oocytes
Background & Aim: Considering that antioxidants are known as effective free radicals scavenger, it may be able to improve the in vitro oocyte maturation and the fetal quality. This study was designed to determine the effect of Gundelia tournefortii leaves (GTE) hydro-alcoholic extract as a source of antioxidant on in vitro oocyte maturation. Experimental: Germinal vasicle (GV) were...
[ 3 ] - تاثیر عصاره الکلی ریشه گیاه(آوندول) Smyrnium cordifolium Boiss در پیشگیری از سنگ کلیه اگزالات کلسیم ناشی از اتیلن گلیکول در موش صحرایی
مقدمه: با توجه به اثبات اثر داروهای گیاهی مختلف در درمان سنگ کلیه، در این مطالعه بررسی اثر عصاره الکلی ریشه گیاه آوندول(Smyrnium cordifolium Boiss) بر روی پیشگیری از سنگ کلیه القاء شده توسط اتیلن گلیکول(EG) در موش صحرایی ماده نژاد ویستار مورد بررسی قرار گرفته است. مواد و روش ها: 32 موش صحرایی ماده نژاد ویستار به طور تصادفی به 4 گروه تقسیم شدند. گروه کنترل آب آشامیدنی و 3 گروه دیگر 1 درصد اتیلن...
[ 4 ] - تاثیر عصاره چای سبز بر میزان توان زیستی و آپوپتوز سلول‌های آدنوکارسینومای پستان انسان رده SKBR3 در مقابل سلول های فیبروبلاست نرمال (HU-02)
Background and Aim: Breast cancer is one of the most common types of cancers and is the second leading cause of death form of cancer in women. In recent years, many scientific and medical studies have shown that Green tea has anti-proliferative, anti-mutagenic, anti-oxidant, antibacterial and antiviral effects. Some Green tea polyphenols have anti-cancer activity. In the present study, the effe...
[ 5 ] - Anti-proliferative and pro-apoptotic effects of gallic acid on the breast adenocarcinoma cell lines SKBR3 versus normal fibroblast cells (HU-02)
Background: Breast cancer is a malignant proliferation of epithelial cells that lining the ducts or lobules of the breast. Breast cancer is the second common cancer (after lung cancer) in women. Gallic acid, being a polyphenols, has been reported for its antiproliferative activity against many cancer cell lines. Objective of the present study is effect of gallic acid on proliferation and apopto...
[ 6 ] - مهار انتخابی رشد رده سلولی آدنوکارسینومای پستان با استفاده از متابولیت‌های تولیدی سویه بومی سودوموناس UW4 در آزمایشگاه
Background: Breast cancer is a malignant proliferation of epithelial cells that lining the ducts or lobules of the breast. It is the second common cancer, after lung cancer in women. Since growth inhibition is an important strategy in cancer treatment, many attempts are in program to find new apoptotic inducer agents. Today there is some reports about effect of metabolites of Pseudomonas on can...
[ 7 ] - القاء آپوپتوز و افزایش بیان ژن‌های P53 و PARP در سلول‌های کارسینومای آناپلاستیک تیروئید انسان (SW-1736) به وسیله کورکومین (Curcumin)
Introdution:. Anaplastic thyroid carcinoma (ATC) is a type of thyroid gland malignancy that originates from the anaplastic cells of this gland. This kind of malignancy is highly invasive and patients have a poor response to treatment. In this study, the effect of curcumin on apoptosis and p53 and PARP genes expression of the human anaplastic thyroid carcinoma cell line (SW-1736) examined. Curcu...
[ 8 ] - بررسی اثر متابولیت های تولیدی سویه بومی Pseudomonas sp UW4 بر بیان ژن p53 در رده سلولی SK-BR-3 سرطان پستان انسان
Introdution: Regarding to the development the problems of systemic toxicity and drug resistance in cancer chemotherapy, the continuing discovery of new bioactive compounds and anticancer agents is very necessary. Therefore, in this study, we checked the anticancer activity of native Pseudomonas sp. UW4 metabolite to find new compound. Methods: This experimental study was performed in Shahrekor...
[ 9 ] - The Beneficial Effect of Hydro-alcoholic Extract of Punica Granatum L. Leaves & Flower on Ethylene Glycol-Induced Kidney Calculi in Rats
Background & Aim: Punica granatum L. (pomegranate) is a widely used plant that has high nutritional value .This study evaluated prevention effect of hydro alcoholic extract of Punica granatum flower and leaves ethylene glycol-induced Nephrolithiasis in Wistar rats. Experimental: 20 male Wistar rats were randomly divided into 4 equal groups. G...
[ 10 ] - Effect of the extract from Gundelia tournefortii on immature mouse oocytes
Background & Aim: Considering that antioxidants are known as effective free radicals scavenger, it may be able to improve the in vitro oocyte maturation and the fetal quality. This study was designed to determine the effect of Gundelia tournefortii leaves (GTE) hydro-alcoholic extract as a source of antioxidant on in vitro oocyte maturation. Experimental: Germinal vasicle (GV) were...
[ 11 ] - In vitro Apoptosis Induction in Prostate Cancer Cells (PC-3) using Bacillus licheniformis Supernatant
Background: Cancer is one of the most common causes of death in humans. Therefore, there is a need for new cytotoxic compounds from natural sources such as native bacteria. The current study aimed at investigating the cytotoxic effects of compounds obtained from gram-positive terricolous bacteria on the apoptosis of cells in prostate cancer (PC-3). Materials & Methods: A total of 70 s...
[ 12 ] - Cytotoxic effect of curcumin on viability and P21 and Bcl-2 genes expression of the human anaplastic thyroid Carcinoma cells line (SW-1736)
Background & Aim: Anaplastic thyroid carcinoma (ATC) is an uncommon malignancy of the thyroid .with poor prognosis and 2 to 6 month of survival time. The aim of this study was to explore the effect of curcumin on bioavailability and expression of p21 and Bcl-2 genes in human anaplastic thyroid carcinoma cell line (SW-1736). Methods: In this study, human anaplastic thyroid carcinoma (SW-1736) c...
[ 13 ] - Effect of citric acid on Bioavailability and apoptosis induction in human colorectal Adenocarcinoma cell line (HT29)
Background and Aim: Colorectal adenocarcinoma is one of the common causes of death due to weak response to common therapies. In this study, the effect of citric acid on bioavailability and apoptosis of the human colorectal adenocarcinoma cell line (HT29) was examined. Citric acid is a naturally organic acid that commonly found in citrus and is considered as a physiological inhibitor of enzymes ...
[ 14 ] - Apoptotic Induction in Human Colorectal Adenocarcinoma Cell Line and Growth Inhibition of Some Gastrointestinal Pathogenic Species by Lactobacillus Sakei Metabolites
Background and Aim: Lactobacillus is the most important genus of lactic acid bacteria and the use of some species of lactobacillus with the probiotic potential can be effective for inhibition of the growth of some pathogens and control of gastrointestinal diseases and cancers. In this study, the pro-apoptotic and antimicrobial effect of Lactobacillus sakei on human colorectal adenocarcinoma c...
[ 15 ] - Cytotoxic and antimicrobial effects of lactobacillus sakei on human colorectal adenocarcinoma cell line (HT29) and some pathogenic microorganisms
Background: Even after surgery, as the most effective treatment for colorectal cancer, about 30-40% of cases are recurring. Since growth inhibition is an important strategy in cancer treatment, many attempts are in the program to find new agents, so in this study, the cytotoxic and antimicrobial effects of Lactobacillus sakei on colon cancer cell line (HT-29) and some pathogenic microorganisms ...
[ 16 ] - Cytotoxic and pro-apoptotic Effects of Spirulina Platensis Extract on PC-3 Prostate Adenocarcinoma Cell Line
Introduction: Prostate cancer is one of the most common cancers among men, with an increasing incidence and mortality rate. In the present study, cytotoxic and pro-apoptotic effects of spirulina platensis extract on PC-3 prostate adenocarcinoma cell line were investigated. Methods: In the present experimental study, the PC-3 prostatic cancer cells were treated in four experimental with 400, ...
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