Mohammadreza Bazrafshani

Assistant Professor, Department of Medical Genetics, Kerman University of Medical Sciences, Kerman, Iran

[ 1 ] - The Relationship between Hepatitis C Genotypes and Viral Load: a study on hepatitis C patients in Kerman, Iran using Real-time PCR

Abstract Background: Distribution of hepatitis C virus genotypes varies geographically and can be associated with clinical aspects. The virus has six major genotypes and eleven sub-genotypes. According to the recent studies, in hepatitis C patients, treatment duration and ribavirin dosage should be determined based on the type of virus genotype. Be...

[ 2 ] - بررسی فراوانی جهش‌های مضاعف شدگی ژنHER2/neu در بیماران مبتلا به سرطان معده با استفاده از تکنیک تکثیر پروب وابسته به الحاق چندتایی

Background and aims:  Gastric malignancies have the fourth place among the most prevalent cancers. In many cancers, overexpressing of HER2/neu gene has been observed with a poor prediction. Up to now, there is a little information about the duplication of HER2/neu gene in gastric cancer using MLPA method. The present study aimed to investigate the frequency of mutations resulting from ampl...

[ 3 ] - بررسی فراوانی آلل‌های HLA-DRB1 و HLA-DQB1 در کودکان مبتلا به ریفلاکس وزیکویورترال اولیه

Background: Vesicoureteral reflux (VUR) is the retrograde flow of urine from the bladder into the ureter and toward the kidney. Vesicoureteral reflux is the most com-mon inherited disease in urogenital system. Primary VUR is the most common urologi-cal anomaly in children and it has been reported in 30-50% of those who present with urinary tract infection (UTI). The association of vesicouretera...