Abbas Ahmadi
Department of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
[ 1 ] - Effect of Satureja khuzestanica essential oil against fertility disorders induced by busulfan in female mice
Busulfan is an alkylating agent affects ovarian follicles growth by oxidative stress induction. Satureja khuzestanica has antioxidant effects. The aim of this study was to examine whether S. khuzestanica essential oil (SKEO) exhibits protective effects on busulfan-induced ovarian failure. Eighty-four adult female mice were divided into six groups including dimethyl sulfoxide (...
[ 2 ] - Protective effect of ethyl pyruvate on mice sperm parameters in phenylhydrazine induced hemolytic anemia
The aim of the present study was to assess the protective effect of ethyl pyruvate (EP) on sperm quality parameters, testosterone level and malondialdehyde (MDA) in phenylhydrazine (PHZ) treated mice. For this purpose, 32 NMRI mice with the age range of 8 to 10 weeks, weight average 26.0 ± 2.0 g, were randomly divided into four equal groups. The control group (1) received normal saline (0. 1 mL...
[ 3 ] - Protective effects of cornus mas extract on in vitro fertilization potential in methotrexate treated male mice
Current study was aimed to evaluating protective effects of cornus mas fruit extract (CMFE) in mice treated with methotrexate (MTX). For this purpose, 48 young mature male mice were divided into 6 groups. Control group received only normal saline (0.1 mLper day, intraperitoneally), and the second group was administered MTX (20 mg kg-1 perweek, intraperitoneally). The third, ...
[ 4 ] - Evaluation of antioxidant effects of crocin on sperm quality in cyclophosphamide treated adult mice
Cyclophosphamide (CP) is one of the anti-neoplastic drugs. Despite its numerous clinical applications, it has devastating effects on the testicles and declines the sperm quality in treated patients. This study was aimed to investigate the protective effect of crocin in improving the toxicity induced by CP in reproductive system. In this study, 24 male adult mice (6 to 8 weeks) were randomly div...
[ 5 ] - Protective effects of vitamin E and Cornus mas fruit extract on methotrexate-induced cytotoxicity in sperms of adult mice
This study was aimed to assess the protective effects of Cornus mas fruit extract (CMFE) and vitamin E (Vit E) on sperm quality parameters in the methotrexate (MTX)-treated mice. Forty-eight young adult male mice (8-12 weeks) were randomly divided into six groups including control and test groups. The control group received normal saline orally , and the test groups were treated MTX (2...
[ 6 ] - اثر لوپئول و فلوتامید بر بهبود هایپرفیبروز رحمی ناشی از تجویز دهیدرواپی‌آندروسترون (DHEA) در موش سفید کوچک آزمایشگاهی
Background & Aims: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive ages that may contribute to uterine complications such as endometrial hyperplasia and hyperfibrosis. Hyperandrogenemia is the key factor in the pathophysiology of PCOS. Based on recent finding concerning anti-androgen effects of Lupeol, we aimed to study the effects of this tr...
[ 7 ] - Effects of chronic low- dose treatment with cyclophosphamide on the rat testis
Introduction: Cyclophosphamide (CP) is used for the treatment of various cancers. In spite of its therapeutic importance, a wide range of adverse effects such as reproductive toxicity has been observed following the administration of this drug in human and experimental animals. In the current study, we have investigated the adverse effects of CP on morphology and histology of testis rats. M...
[ 8 ] - Investigation of the effect of experimental polycystic ovarian syndrome induced by stradiolvalerate on oocyte quality and in vitro fertilization potential and evaluation of vitamin E supplementation to emryo culture in mouse model
Background & Aims: One of the most common causes of infertility in women is ovarian causes, especially polycystic ovary syndrome (PCOS). However, in patient with PCOS, the number of oocytes taken increased during the IVF, but these oocytes have often low quality, which ultimately leads to reduce fertilization potential. The aim of this research was investigation of PCOS on oocytes quality and p...
[ 9 ] - مطالعه اثر عصاره هیدروالکلی ریشه گیاه شیرین بیان در بهبود باروری موش‌های سوری مبتلا به هایپرآندروژنیسم ناشی از سندروم تخمدان پلیکیستیک تجربی ایجاد شده توسط لتروزول.
زمینه و هدف: سندرم تخمدان پلیکیستیک (PCOS) شایعترین اختلال غدد درونریز در زنان میباشد. این سندرم با علایم افزایش هورمونهای آندروژنی، عدم تخمکگذاری، ناباروری و چاقی مشخص میگردد. مهمترین نشانه برای وجود تخمدان پلیسیستیک، افزایش آندروژنهای خونی میباشد. هدف از این تحقیق بررسی اثر عصاره هیدروالکلی ریشه شیرین بیان بر عوارض هایپرآندروژنیسم ایجاد شده توسط تخمدان پلی کیستیک تجربی بر توان بارو...
[ 10 ] - تأثیر آنتی‌اکسیدانتی مرزه خوزستانی بر باروری و رشد جنین‌های حاصل از لقاح داخل آزمایشگاهی موش‌های سوری نر بالغ تحت درمان با نانیل‌فنل
زمینه و هدف: نونیل‌فنل نوعی از مواد شیمیایی محیطی است که مانند هورمون آندروژن عمل کرده و مانع از فعالیت هورمون‌ها، سبب ایجاد اختلالات سیستم تولیدمثلی و القای استرس اکسیداتیو می‌شود. در این مطالعه اثر محافظتی مرزه خوزستانی بر روی لقاح داخل آزمایشگاهی موش سوری نر بالغ تیمارشده با نونیل‌فنل بررسی گردید. روش بررسی: در این مطالعه تجربی، تعداد 24 عدد موش سوری نر بالغ 8 هفته‌ای، به‌طور تصادفی انتخاب و...
[ 11 ] - Protective effect of ethyl pyruvate on testicular histology and fertilization potential in cyclophosphamide treated mice
In the present study, we aimed to address the use of ethyl pyruvate (EP) against the harmful effects of cyclophosphamide (CP) treatment. Thirty-nine adult male mice were divided into three groups including control group received normal saline [0.20 mL per day; intraperitoneally (IP)], CP group received CP (15.00 mg kg-1 per week, IP) and CP+EP group received EP (40.00 mg kg-1</s...
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