Zahra Bakhtiary
Department of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
[ 1 ] - Evaluation of antioxidant effects of crocin on sperm quality in cyclophosphamide treated adult mice
Cyclophosphamide (CP) is one of the anti-neoplastic drugs. Despite its numerous clinical applications, it has devastating effects on the testicles and declines the sperm quality in treated patients. This study was aimed to investigate the protective effect of crocin in improving the toxicity induced by CP in reproductive system. In this study, 24 male adult mice (6 to 8 weeks) were randomly div...
[ 2 ] - ارزیابی اثر محافظتی کروسین بر آسیب DNA اسپرم و لقاح داخل آزمایشگاهی موش های نر بالغ تحت درمان با سیکلوفسفامید
Background and purpose: Oxidative stress induced by cyclophosphamide (CP), a chemotherapeutic agent, causes vulnerability of sperm and declining the fertility power. Then in this study the effect of crocin (saffron extract) on amelioration of these side effects was investigated. Materials and methods: In this study 24 adult male mice were divided in three groups (n=8). Control group received n...
[ 3 ] - Protective effect of ethyl pyruvate on testicular histology and fertilization potential in cyclophosphamide treated mice
In the present study, we aimed to address the use of ethyl pyruvate (EP) against the harmful effects of cyclophosphamide (CP) treatment. Thirty-nine adult male mice were divided into three groups including control group received normal saline [0.20 mL per day; intraperitoneally (IP)], CP group received CP (15.00 mg kg-1 per week, IP) and CP+EP group received EP (40.00 mg kg-1</s...
[ 4 ] - Ethyl Pyruvate Ameliorates The Damage Induced by Cyclophosphamide on Adult Mice Testes
Objective Cyclophosphamide (CP) is a chemotherapy drug which causes deleterious effects on testicular tissue and increases free radicals in the body. The aim of this study is to investigate the protective effects of ethyl pyruvate (EP) on testicular improvement in CP treated animals. MaterialsAndMethods In this experimental study, 15 male mice (6-8 weeks) were divided into 3 groups. The control...
[ 5 ] - P-2: Protective Effects of Ethyl Pyruvate on Serum Antioxidant Capacity and Testis Germinalepithelium Morphometryin Cyclophosphamide Treated Mice
Background Cyclophosphamide (CP) is a chemotherapeuticdrug which causes deleterious effects on tissue of testicle and increases free radicals in the body. The aim of this study is to investigate protective effects of ethyl pyruvate (EP) on improvement of testicle inCP treated animals. MaterialsAndMethods In this study, 15 male mice(6-8 weeks) were divided into 3 groups. Control group receivedno...
[ 6 ] - P-33: Ameliorative Effects of Ethyl Pyruvate on Testis Histochemistry, Serum Superoxide Dismutase and Testosterone in Chemotherapeutic Mice
Background Infertility and fertility decline are quite a conundrum for medicine, rampant among 10-15 percent of couples. In about 40 percent of cases, men are the main culprit. Since sperm production disorders are the focal cause of man infertility, insights into these disorders and taking action to ameliorate the situation is quite vital. The current study concentrates on infertility due to sp...
[ 7 ] - P-34: Crocin Ameliorate The In Vitro Fertilization (IVF) in Mice Treated with Cyclophosphamide
Background Oxidative stress induced by cyclophosphamide (CP), as a chemotherapeutic agent, causes vulnerability of sperm and declining the fertility capacity. Then in this study the effect of crocin (saffron extract) on amelioration of these side effects was investigated. MaterialsAndMethods In this study 24 mice were divided in three groups (n=8). Control group received normal saline (0.2 ml/d...
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