Nahid Masoudi
Department of Biology, Islamic Azad University, Damghan Branch, Iran
[ 1 ] - Association of rs12108497 (Caspase 3 Gene) Polymorphism in Gastric Cancer Patients in Sari
Gastric cancer is the fourth most common cause of malignancy death in the world, which also has a high prevalence in Iran. Caspase 3 gene is considered one of the major genes related to gastric cancer. The present study aimed to investigate the relationship between rs12108497 polymorphism of Caspase 3 gene. Due to the fundamental role of caspases, we have considered an SNP of Caspase 3 (common ...
[ 2 ] - Investigating the Distribution of ERCC2 (rs13181) Gene Polymorphism in Gastric Cancer Patients in Mazandaran: A Case-control Study
Background and objectives: Gastric cancer is one of the most common cancers of the gastrointestinal tract in the world, which also has a high prevalence in Iran. ERCC2 gene is considered one of the major genes related to gastric cancer. The present study aimed to investigate the relationship between rs13181 polymorphism of ERCC2 gene. The polymorphism in the promoter region of ERCC2 gene can af...
[ 3 ] - بررسی اثرات سلولی نارنجین برپیشگیری از سمیت ژنتیکی ناشی از میفه پریستون بر روی لنفوسیت های خون محیطی انسان
Background and purpose: Mifepristone is an oral synthetic steroid with antiglucocorticoid and antiprogesterone activities. Therefore, it could be dangerous during pregnancy since it causes cytogenetic damage and, consequently, abortion. Flavonoid compounds such as naringin have antioxidant properties and eliminate various free radicals. Naringin is abundantly found in Iran, so, we investigated ...
[ 4 ] - بررسی پراکندگی پلی مورفیسم ژن TCF7L2 (rs7903146) در بیماران دیابتی نوع 2 در غرب مازندران ایران
مقدمه: دیابت نوع 2 یک گروه ناهمگن پیچیده ای از شرایط متابولیکی است که با افزایش سطح قند خون به علت اختلال در عملکرد انسولین و یا ترشح انسولین توصیف می شود. ژن TCF7L2 به عنوان یکی از ژنهای عمده مستعد ابتلا به دیابت در نظر گرفته شده است. پلی مورفیسم تک نوکلئوتیدی rs7903146 واقع در اینترون شماره 3 این ژن می باشد که به طور قابل توجهی با دیابت نوع 2 موثر است. مواد و روش‌ها: در این مطالعه ی مورد – ش...
[ 5 ] - Effects of Flaxseed (Linum Usitatissimum L.) against Genotoxicity Induced by Cyclophosphamide on Human Blood Lymphocyte
Introduction: Medicinal plants, such as flaxseeds play an important role in the health of individuals and communities. Regarding the phytochemical properties of flaxseed, this study aimed to investigate the hydroalcoholic effects of this plant on the genetic toxicity of cyclophosphamide in peripheral blood lymphocytes. Materials & Methods: The flaxseed extract was initially prepared by macer...
[ 6 ] - Effect of Aerobic and Resistance Training on GDF-15 Levels in Patients with Type 1 Diabetes
Background and purpose: Increasing prevalence of diabetes and its complications, including cardiovascular problems increase the cost of health care which could be diminished with proper planning to change lifestyle. The present study investigated the effect of aerobic and resistance trainings on blood GDF15 level as a protective marker on cardiovascular cells in patients with type 1 diabetes. ...
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