علیزاده, اکرم

[ 1 ] - بررسی اثر لیتیوم کلراید در القای سلول‌های استرومایی مغز استخوان به سلول‌هایی با فنوتیپ عصبی

  Background & Objective : Bone marrow stromal cells (BMSCs) are a kind of stem cells with high pluripotency. The BMSCs can differentiate into mesodermal and non mesodermal cells. Because of availability of them, they are a suitable source of adult stem cells for cell therapy. Some inducers were used to differentiate stem cells into neural phenotype, such: retinoic acid, dimethyl sulfoxide, dep...

[ 2 ] - The Role of Microgravity in Cancer: A Dual-edge Sword

Since human beings could travel beyond the earth atmosphere, scientists started to investigate the effect of microgravity on human cells. Microgravity has different effects on normal and cancer cells, but the related mechanisms are not well-known till now. The aim of the present review is to focus on the consequences of exposing the cancer cells to reduced gravity. Some cancer cells organize th...

[ 3 ] - The Role of Microgravity in Cancer: A Dual-edge Sword

Since human beings could travel beyond the earth atmosphere, scientists started to investigate the effect of microgravity on human cells. Microgravity has different effects on normal and cancer cells, but the related mechanisms are not well-known till now. The aim of the present review is to focus on the consequences of exposing the cancer cells to reduced gravity. Some cancer cells organize th...

[ 4 ] - مروری برمهمترین کاربردهای زیست فناوری و مباحث اخلاقی پیرامون آن

زمینه و هدف: پیشرفت‌های اخیر در مهندسی ژنتیک و زیست‌فناوری امکانات جدیدی در اختیار بشر قرار داده است تا بتواند به دستکاری ژنتیکی و تغییر هر شکلی از حیات بپردازد. این فناوری کاربردهای بسیار سودمندی در پزشکی، داروسازی، کشاورزی و صنایع دارد. مهم‌ترین کاربردهای زیست‌فناوری عبارت‌اند از: اصلاح ویژگی‌های وراثتی گیاهان و دام‌ها، تولید داروها در بیورآکتورهای زنده، ایجاد مدل‌ها و الگوهایی برای مطالعه بی...

[ 5 ] - Comparing the Impact of Long-Term Exposure to Extremely Low-Frequency Electromagnetic Fields With Diverse Values on Anxiety, Memory, Learning, and Β-Amyloid Deposition in Adult Rats

Background: Extremely low-frequency electromagnetic fields (ELF-EMFs) have gathered significant consideration for their possible pathogenicity. However, their effects on nervous system functions were not fully clarified. In this study, our aim was to assay the effect of ELF-EMFs with different intensity on memory, anxiety, antioxidant activity, beta amyloid (Aβ) deposition and microglia populat...

[ 6 ] - The Effect of Rosmarinic Acid in Neural Differentiation of Wartons Jelly-derived Mesenchymal Stem Cells in Two Dimensional and Three Dimensional Cultures using Chitosan-based Hydrogel

Numerous studies have shown the positive effects of rosmarinic acid on the nervous system. Rosmarinic acid as a herbal compound with anti-inflammatory effects can prevent the destructive effect of inflammation on the nervous system. Furthermore, various studies have emphasized the advantages of three dimensional (3D) culture over the two dimensional (2D) culture of cells. In this study, thermos...