حسینی, عبدالکریم

گروه فیزیولوژی، دانشکده علوم زیستی، دانشگاه شهید‏بهشتی، تهران، ایران

[ 1 ] - اثر عصاره الکلی گیاه مریم ‏گلی (Salvia officinale) بر کاهش درد ناشی از هیوسین در موش‏های صحرایی نر بالغ نژاد ویستار

زمینه و هدف: هیوسین (اسکوپولامین) که داروی آنتی کولینرژیک و ضددرد محسوب می شود، دارای بعضی عوارض جانبی می‏باشد. اخیراً توجه زیادی به تداخل بین داروهای صناعی و عصاره ‏های گیاهی در ایجاد پاسخ‌های فارماکولوژیک شده که امکان استفاده از حداقل دوز و عوارض جانبی را فراهم می کند. در این پژوهش اثر تجویز عصاره مریم ‏گلی، هیوسین و ترکیب مریم‏ گلی و هیوسین بر کنترل درد در موش‌های صحرایی مورد بررسی قرار گرفت....

[ 2 ] - The involvement of kisspeptin in centrally regulatory mechanism of neuropeptide Y on testosterone secretion in male Wistar rats

Introduction: Numerous studies have demonstrated that kisspeptin, a peptide from the KISS1 gene, plays an important role in regulating the secretion of gonadotropin releasing hormone (GnRH). Also, there is some evidence suggesting that kisspeptin can interact with other neuropeptides for the control of the reproductive axis. In the present study, we have investigated the effect of central admin...

[ 3 ] - Protective effect of ginger against the pentylenetetrazole-induced seizure threshold model in streptozocin treated-diabetic mice

Introduction: There is evidence that diabetes affects seizure susceptibility. Ginger (Zingiber officinale Roscoe) which is used in traditional medicine has antioxidant activity and neuroprotective effects. The aim of this study was to evaluate the seizure threshold induced by pentylenetetrazole (PTZ) in diabetic mice after induction of diabetes with streptozocin and to examine the possible ...

[ 4 ] - بررسی تاثیر عصارۀ برگ گیاه سنجد (Elaegnus angustifolia L.) بر پروفایل لیپیدمی موش‌های صحرایی

Background: Hyperlipidemia is one of risk factor in cardiovascular diseases, with regard to possible effect of Elaegnus angustifolia this study aimed at evaluating the effect of E. angustifolia leaf extract on lipid profiles in normal and fed with hyperlipidemic diet rats which was conducted in 2014 in the laboratory of the Faculty of Science, Islamic Azad University of Hamedan. Materials and m...

[ 5 ] - The Anxiolytic and Antidepressant Effect of Tanacetum polycephalum in the Pentylenetetrazole Kindled Rats

Background and objective: Epilepsy one the most prevalent neurological illness which affects behavioral statuses like anxiety, depression and balance. Based on the anti-inflammatory and antioxidant properties of Tanacetum polycephalum, its effect on anxiety and depression caused by pentylenetetrazole (PTZ)-kindling in rats was investigated. Methods : In order to prepare the required extract, ae...