هاشمپور, طیبه
مرکز تحقیقات میکروب شناسی بالینی، بیمارستان نمازی، دانشگاه علوم پزشکی شیراز، شیراز، ایران
[ 1 ] - مقایسه فراوانی ژنوتیپ مطلوب ژن اینترلوکین 28B در افراد سالم و بیماران آلوده به HCV
مقدمه: درمان عفونت مزمن ویروس هپاتیت C (Hepatitis C virus; HCV) با استفاده از ترکیب دارویی اینترفرون آلفا(Interferon-α; IFN-α) و ریباویرین(Ribavirin; RBV) صورت می گیرد. عوامل مختلفی در میزان پاسخ به درمان بیماران آلوده به HCV نقش دارند که ژنوتیپ و میزان بار ویروس، سن، نژاد، چاقی، مقاومت به انسولین، میزان فیبروز و پلی مورفیسم های ژن اینترلوکین 28B (Interleukin 28B; IL-28B) مهم ترین آن ها هستند...
[ 2 ] - Embryonic Toxico-pathological Effects of Origanum vulgare: Evaluation of the Gross and Histopathological Lesions using a Chick Embryo Model
Background & Objective: Toxico-pathological effects of herbal plants have always been a major concern, but little information is provided on the toxico-pathological effects of origanum on the fetus. Due to ethical rules and regulations, no drug experiment on the human fetus is permitted; hence, the chick embryo model is used as an ideal opportunity to study the adverse effects of drugs. This ...
[ 3 ] - The role of Iranian medicinal plants in experimental surgical skin wound healing: An integrative review
Objective(s): Wounds are physical injuries that cause a disturbance in the normal skin anatomy and function. Also, it has a severe impact on the cost of health care. Wound healing in human and mammalian species is similar and contains a complex and dynamic process consisting of four phases for restoring skin cellular structures and tissue layers. Today, therapeutic app...
[ 4 ] - Studying the Frequency of Favorable Allele of rs12979860 Polymorphism of IL-28B in Healthy and HCV Infected Iranian Individuals
Background & Objective: Hepatitis C Virus (HCV) is one of the important risk factors for liver cirrhosis and hepatocellular carcinoma. Some of the host genetic factors such as interleukin 28B (IL-28B) may influence the response to the antiviral therapy. IL28B is a member of the interferon (IFN) family which causes an antiviral response. Previous studies indicated that rs12979860 polymorphisms o...
[ 5 ] - A Study on the Effects of Perovskia abrotanoides Karel on Experimental Skin Burn in Male Rat: in-vivo and in-vitro Findings
Background & Objective: Perovskia abrotanoides Karel locally known as Brazambal, is widely used in medical practice to treat various disorders. Burn is a common source of injury and Brazambal ointment has been extensively used in burn wound healing in North of Iran. The purpose of this study was to examine the healing effect of Brazambal ointment in experimental model of burn. In addition, in-...
[ 6 ] - Utilization of a chicken embryo membrane model for evaluation of embryonic vascular toxicity of Dorema ammoniacum
Objective: Extensive research has been done to assess the efficacy of herbs for treating different disorders. Dorema ammoniacum (D. ammoniacum) is used in folk medicines for various goals. The application of herbs in medicine is accompanied by harmful effects. Chick embryo is considered a suitable model for assessing drugs toxicity. The present study aimed to evaluate the chang...
[ 7 ] - The role of labeled cell therapy with and without scaffold in early excision burn wounds in a rat animal model
Objective(s): One of the essential problems in burn therapy is performing the permanent replacement of skin in full and deep thickness injuries. Human Wharton’s Jelly mesenchymal stem cells (HWJMSCs) have a unique combination of prenatal and postnatal properties. Decellularized human amniotic membrane (DHAM) can be used as a scaffold for HWJMSCs-therapy. We aimed to ev...
[ 8 ] - Comparison of the prevalence of HBV, HCV, HIV, CMV and EBV infections in patients with systemic lupus erythromatosus and healthy population
Background: Systemic lupus erythematosus is a systemic autoimmune disease that affects almost all organs of the body, and viral infections are involved in its development and progression. The present study aimed to evaluate the serological status of some viral infections in patients with systemic lupus erythematosus and a healthy population. Methods: This descriptive study conducted from May 2...
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