بوالحسنی, اعظم

دانشیار، بخش هپاتیت و ایدز، انستیتو پاستور ایران، تهران، ایران . دانشیار، مرکز درمان جامع هموفیلی ایران، تهران، ایران

[ 1 ] - بررسی پلی‌مورفیسم ژن‌ های IGSF2 و TNFα و خطر توسعه مهار کننده در بیماران مبتلا به هموفیلی A

Background and purpose: Hemophilia is a hereditary X-linked disorder. Females are carriers and males have the disorder. Hemophilia A is caused by deficiency in the production of factor VIII. In some hemophilia patients, inhibitors including IgG1 and IgG4 antibodies are expressed against this factor. These inhibitors interact with factor VIII and suppress its function. The current study aimed at...

[ 2 ] - Evaluation of Cell Penetrating Peptide Delivery System on HPV16E7 Expression in Three Types of Cell Line

Background: The poor permeability of the plasma and nuclear membranes to DNA plasmids are two major barriers for the development of these therapeutic molecules. Therefore, success in gene therapy approaches depends on the development of efficient and safe non-viral delivery systems. Objectives: The aim of this study was to investigate the in vitro delivery of plasmid DNA encoding HPV16 E7 gene...

نویسندگان همکار