Mahdi Khorsand

Department of Physiology, Faculty of Medical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

[ 1 ] - P130: The Role of Rho-Kinase (ROCK) in Microglia/Macrophage Polarization in Neuroinflammatory Diseases

Macrophage/microglia with heterogonous phenotype and function under physiological and pathological conditions are the main cell lineage involved in inducing immune responses in neuroinflammatory diseases which exhibit combined inflammatory and anti-inflammatory functions. An increase in the expression of iNOS triggers M1 phenotype that secrete high concentrations of inflammatory cytokines, whil...

نویسندگان همکار