Farid Abolhassani

Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

[ 1 ] - Methylation Status of H19/IGF2 Differentially Methylated Region in in vitro Human Blastocysts Donated by Healthy Couples

Backgrund: Imprinted genes are a unique subset of few genes, which have been differentially methylated region (DMR) in a parental origin-dependent manner during gametogenesis, and these genes are highly protected during pre-implantation epigenetic reprogramming. Several studies heve shown that the particular vulnerability of imprinting genes during suboptimal pre- and peri-conception microenvir...

[ 2 ] - نقش سلول‌های سرتولی در تعیین سرنوشت سلول‌های بنیادی اسپرماتوگونی

Background: Spermatogenesis is a complex and highly organized process of proliferation and differentiation of spermatogonial stem cells. Spermatogonial stem cells (SSCs) as a unique stem cell have the potential to self-renewal, differentiation and transmit genetic information to the next generation and play a vital role in maintaining fertility. Sertoli cells as the only somatic cells within th...

[ 3 ] - Flaxseed Can Reduce Hypoxia-Induced Damages in Rat Testes

Introduction: Hypoxia is a common leading cause of detrimental effect on structure and function of tissue during increase in the production of reactive oxygen species that are generated during the re-oxygenation phase of intermittent continuous hypobaric hypoxia and contribute to physiological responses. This study was carried out to evaluate the effects of flaxseed (Fx) in reducing the inciden...

[ 4 ] - O-20: The Combination of Basic Fibroblast Growth Factor and Follicular Stimulating Hormone Promotes Human Follicle Development In Vitro Culture

Background Fertility preservation is an important part of scientific study in the field of reproductive medicine. Ovarian cryopreservation and in vitro follicles culture provide option for fertility conservation in older women or cancer patients. Basic fibroblast growth factor (bFGF) or FGF-2, is member of fibroblast growth factors family which play critical roles in cell migration proliferatio...

[ 5 ] - P-52: Brain-Derived Neurotrophic Factor Promotes The Development of Human Ovarian Early Follicles during Growth In Vitro

Background Cryopreservation of ovarian cortex is increasingly used to preserve fertility before cancer therapy. Recently, studies show that Brain-derived neurotrophic factor (BDNF) may be involved in oocyte maturation. Brain-derived neurotrophic factor (BDNF) is member of neurotrophin family that has anti-apoptotic effects on nervous system. Recent researches show that it also plays key role in...

[ 6 ] - P-97: The Effects of Catalase Addition to The Cryopreservation Medium on Follicles Apoptosis and Oxidative Stress in Human

Background Today, cryopreservation of ovarian tissue has been the effective procedure to restore fertility in can cer patients. It is well known that oxidative stress (OS) is a widespread phenomenon that occurs in ovary cryopreservation. Numerous studies show that follicular atresia in mammalian species due to the accumulation of toxic metabolites often results from oxidative stress. Therefore,...

[ 7 ] - Onm-3: Ginseng and Male Reproductive Function

Background Ginseng is often referred to as the King of all herbs, and is found to be a promising agent to improve general well-being. Ginseng has also been reputed as an aphrodisiac, a disused to treat sexual dysfunction as well as to enhance sexual behavior. MaterialsAndMethods In this trial, thirty three adult male rats were divided into three groups. Experimental groups received gensing oral...