Mohammad Hossein Boskabady

[ 1 ] - Antihistaminic Effect of Bunium persicum on Guinea Pig Tracheal Chains

In a previous study, the relaxant and anticholinergic (functional antagonism) effects of Bunium persicum (B. persicum ) have been demonstrated on guinea pig tracheal chains. To elucidate the other mechanisms responsible for this relaxant effect, the inhibitory effect of this plant on histamine H1 receptors was examined in this study. The antihistaminic effects of aqueous and macerated extracts,...

[ 2 ] - Effect of vitamin C on tracheal responsiveness and pulmonary inflammation in chronic obstructive pulmonary disease model of guinea pig

Introduction: In the present study, the prophylactic effect of vitamin C, as a potent anti-oxidant, on tracheal responsiveness to methacholine and ovalbumin, bronchoalveolar lavage fluid white blood cell (WBC) count and differential count, and also lung pathology in chronic obstructive pulmonary disease (COPD) -guinea pigs (cigarette exposed guinea pigs) were examined. In addition, the relax...

[ 3 ] - Comparison of Antitussive Effect of Nigella Sativa with Codeine in Guinea Pig

Background:The relaxant and anticholinergic (functional antagonism) effects, histamine H1 inhibitory effect, and calcium channel blocking effect of Nigella sativa have been demonstrated on guinea pig tracheal chains.  Several therapeutic effects including anti-asthma and dyspnea have also been ascribed to the seeds of Nigella sativa. Objective: To evaluate the antitussive effect of this plant. ...