M GHAZI-KHANSARI

the Departments of Pharmacology School of Medicine, Tehran University of Medical Sciences, Tehran, I.R. Iran

[ 1 ] - *Correspondence: M. Ghazi-Khansari. Ph.D., Department ofPharmacology,

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a by-product o f t he trichlorophenol (herbicide) production and is also produced through a variety of combustion processes. It appears that TCDD is a ubiquitous chemical, particularly in industrialised countries, and the liver is the target organ of its toxicity. The prominent hepatotoxic effect of TCDD is progressive centrilobular necrosis. Th...

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