ابوالحسن شاهزاده فاضلی

ibrc

[ 1 ] - بررسی اثر متیل جاسمونات، نیترات پتاسیم و موالونیک اسید بر محتوای آرتمیزین در کشت سوسپانسیون سلولی درمنه خزری

مقدمه: درمنه خزری (Artemisia annua L.) از گیاهان دارویی و معطر خانواده Asteraceae می‌‌‌باشد. اهمیت عمده این گیاه ناشی از حضور لاکتون سزکوئی ترپن اندوپراکسید به نام آرتمیزینین است که علاوه بر خاصیت ضد‌ مالاریایی قادر به از بین بردن انتخابی سلولهای سرطانی می‌باشد.هدف: با توجه به مقدار اندک آرتمیزینین در این گیاه و غیراقتصادی بودن ساخت شیمیایی آن، کشت بافت آن به منظور تولید آرتمیزینین ضروری به نظر...

[ 2 ] - Isolation, purification and identification of three diatom species (Bacillariophyceae) from Gomishan wetland (N. Iran) using phylogeny and silica cell wall ultra-structure analysis

Diatoms of Gomishan wetland (Golestan province, N. Iran), one of the most significant habitats in the eastern shore of the Caspian Sea, has been isolated, purified and identified during 2013. Using serial dilution and streaking on F/2 medium, pure, monoalgal and axenic cultures of the isolates were prepared. The isolates were characterized and identified using micro-morphological studies on the...

[ 3 ] - Isolation, morphological and molecular identification of Dunaliella species in Hoz-e Soltan and Aran-va-Bidgol salt Lakes (Iran)

In this study, Dunaliella has been isolated in Jun. 2014 from Hoz-e Soltan and Aran-va-Bidgol salt Lakes (Iran). The isolates have been identified morphologically with the aid of simple light and invert microscope after isolation and purification on their specific medium (Moh202). By using molecular techniques such as polymerase chain reaction (PCR) and amplification of 18S rDNA gene primers, f...

[ 4 ] - تنوع زیستی باکتری های نمک دوست و تحمل کننده نمک سواحل غربی دریاچه ارومیه

مقدمه: دریاچه ارومیه واقع در شمال ‌غربی ایران بزرگ‏ترین دریاچه دائمی ایران و یکی از سه دریاچه شور دائمی در سطح جهان است. از چهار منطقه غربی این دریاچه نمونه‌برداری انجام شد و تنوع میکروارگانیسم‌ها با روش‌های مبتنی بر کشت و مستقل از کشت بررسی شد. مواد و روش‏‏ها: در روش مبتنی بر کشت، باکتری‏های هالوفیل و هالوتالرنت در شرایط هوازی در چهار محیط کشت‌ MH، SWN، SWNLN و MHLN جداسازی شدند. جدایه‌ها بر ا...

[ 5 ] - Supernatant Metabolites from Halophilic Archaea to Reduce Tumorigenesis in Prostate Cancer In-vitro and In-vivo

Halophilic archaea are known as the novel producers of natural products and their supernatant metabolites could have cytotoxic effects on cancer cells. In the present study, we screened the anticancer potential of supernatant metabolites from eight native haloarchaeal strains obtained from a culture collection in Iran. Five human cancer cell lines including breast, lung, prostate and also human...

[ 6 ] - Supernatant Metabolites from Halophilic Archaea to Reduce Tumorigenesis in Prostate Cancer In-vitro and In-vivo

Halophilic archaea are known as the novel producers of natural products and their supernatant metabolites could have cytotoxic effects on cancer cells. In the present study, we screened the anticancer potential of supernatant metabolites from eight native haloarchaeal strains obtained from a culture collection in Iran. Five human cancer cell lines including breast, lung, prostate and also human...

[ 7 ] - Congenital Malformations in Singleton Infants Conceived by Assisted Reproductive Technologies and Singleton Infants by Natural Conception in Tehran, Iran

Objective Multiple pregnancies occur more frequently in assisted reproductive technology (ART) compared to normal conception (NC). It is known that the risk of congenital malformations in a multiple pregnancy are higher than single pregnancy. The aim of this study is to compare congenital malformations in singleton infants conceived by ART to singleton infants conceived naturally. MaterialsAndM...

[ 8 ] - Association of Two Polymorphisms in H2B.W Gene with Azoospermia and Severe Oligozoospermia in An Iranian Population

Background During spermatogenesis, the H2B family, member W (H2B.W) gene, encodes a testis specific histone that is co-localized with telomeric sequences and has the potential role to mediate the sperm-specific chromatin remodeling. Previously H2B.W genetic variants were reported to be involved in susceptibility to spermatogenesis impairment. In the present study, two single nucleotide polymorp...