صدیقی گیلانی, محمد علی
پژوهشگاه رویان، پژوهشکده زیستشناسی و علومپزشکی تولیدمثل جهاد دانشگاهی، مرکز تحقیقات پزشکی تولیدمثل، گروه آندرولوژی
[ 1 ] - ارزش پیشبینی کننده پارامترهای منی و سن زن و شوهر در نتایج حاملگی با استفاده از روش IUI
Background: Intrauterine insemination (IUI) is one the most common methods in infertility treatment, but its efficiency in infertile couples with male factor is controversial. This study is a retrospective study about correlation between semen parameters and male and female age with successful rate of IUI in patients attending to Royan Institute.Methods: A total of 998 consecutive couples in a ...
[ 2 ] - Detection of Partial AZFc Microdeletions in Azoospermic Infertile Men Is Not Informative of MicroTESE Outcome
Objective microdeletions of Yq chromosome are the most frequent molecular genetics etiology for the male infertility which usually spans AZFa (azoo spermia factor a), AZFb and AZFc regions. Microdeletions are mostly seen in AZFc region and usually cover genes actively involved in spermatogenesis. Partial AZFc microdeletion may also happen with various spans namely gr/gr, b2/b3 and b1/b3. It is ...
[ 3 ] - Varicocelectomy May Improve Results for Sperm Retrieval and Pregnancy Rate in Non-Obstructive Azoospermic Men
Objective Improvement in sperm density and motility after varicocelectomy have been widely reported for men with oligoasthenoteratospermia (OAT),However the value of varicocelectomy in azoospermic men remain controversial.In this study we have evaluated the outcome of microsurgical varicocelectomy in nonobstructive azoospermic (NOA) men with clinical varicocele in five years in royan institute....
[ 4 ] - Effects of Varicocelectomy on Serum Testosterone Levels among Infertile Men with Varicocele
Objective The main purpose of this study is to evaluate the effects of varicocelectomy on serum testosterone levels and semen quality in infertile men who suffer from varicocele. MaterialsAndMethods This prospective study enrolled 115 subjects with clinical varicocele grades II and III and 240 fertile men as the control group. Total volume of testosterone serum level (ng/dl) and semen quality w...
[ 5 ] - Sperm Retrieval in Patients with Klinefelter Syndrome: A Skewed Regression Model Analysis
Background The most common chromosomal abnormality due to non-obstructive azoospermia (NOA) is Klinefelter syndrome (KS) which occurs in 1-1.72 out of 500-1000 male infants. The probability of retrieving sperm as the outcome could be asymmetrically different between patients with and without KS, therefore logistic regression analysis is not a well-qualified test for this type of data. This stud...
[ 6 ] - The Effects of Testosterone on Oxidative Stress Markers in Mice with Spinal Cord Injuries
Objective Spinal cord injury (SCI) causes infertility in male patients through erectile dysfunction, ejaculatory dysfunction, semen and hormone abnormalities. Oxidative stress (OS) is involved in poor semen quality and subsequent infertility in males with SCI. The aim of this study is to examine the effects of SCI on the level of testosterone hormone. MaterialsAndMethods In this experimental st...
[ 7 ] - Association of Two Polymorphisms in H2B.W Gene with Azoospermia and Severe Oligozoospermia in An Iranian Population
Background During spermatogenesis, the H2B family, member W (H2B.W) gene, encodes a testis specific histone that is co-localized with telomeric sequences and has the potential role to mediate the sperm-specific chromatin remodeling. Previously H2B.W genetic variants were reported to be involved in susceptibility to spermatogenesis impairment. In the present study, two single nucleotide polymorp...
[ 8 ] - Predictive Factors of Successful Microdissection Testicular Sperm Extraction in Patients with Presumed Sertoli Cell-Only Syndrome
Background To evaluate predictive factors of successful microdissection-testicular sperm extraction (MD-TESE) in patients with presumed Sertoli cell-only syndrome (SCOS). MaterialsAndMethods In this retrospective analysis, 874 men with non-obstructive azoospermia (NOA), among whom 148 individuals with diagnosis of SCOS in prior biopsy, underwent MD-TESE at Department of Andrology, Royan Institu...
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